Electro-catalysis on H2O2 reduction of electrode capped by nanotubes-polypyrrole composite with hemoglobin integration

Xu, Jingwen; Ma, Ting-Mei; Zhang, Mi; Zeng, Han

doi:10.1007/s10854-021-05326-6

Cited by 5 publications

(1 citation statement)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The direct electrochemistry of redox enzymes or redox proteins can be used for the investigation of the electron transfer mechanism in the biological system, which broadens its applications in areas such as disease diagnosis, biosensing, etc. [1,2]. As a type of glycoprotein with iron porphyrin as the electroactive center [3], horseradish peroxidase (HRP) has been widely used in electrochemical biosensors.…”

Section: Introductionmentioning

confidence: 99%

Preparation and Application of Electrochemical Horseradish Peroxidase Sensor Based on a Black Phosphorene and Single-Walled Carbon Nanotubes Nanocomposite

Wang

et al. 2022

Molecules

View full text Add to dashboard Cite

To design a new electrochemical horseradish peroxidase (HRP) biosensor with excellent analytical performance, black phosphorene (BP) nanosheets and single-walled carbon nanotubes (SWCNTs) nanocomposites were used as the modifier, with a carbon ionic liquid electrode (CILE) as the substrate electrode. The SWCNTs-BP nanocomposite was synthesized by a simple in situ mixing procedure and modified on the CILE surface by the direct casting method. Then HRP was immobilized on the modified electrode with Nafion film. The electrocatalysis of this electrochemical HRP biosensor to various targets was further explored. Experimental results indicated that the direct electrochemistry of HRP was realized with a pair of symmetric and quasi-reversible redox peaks appeared, which was due to the presence of SWCNTs-BP on the surface of CILE, exhibiting synergistic effects with high electrical conductivity and good biocompatibility. Excellent electrocatalytic activity to trichloroacetic acid (TCA), sodium nitrite (NaNO2), and hydrogen peroxide (H2O2) were realized, with a wide linear range and a low detection limit. Different real samples, such as a medical facial peel solution, the soak water of pickled vegetables, and a 3% H2O2 disinfectant, were further analyzed, with satisfactory results, further proving the potential practical applications for the electrochemical biosensor.

show abstract

Section: Introductionmentioning

confidence: 99%