Electroacupuncture in fibromyalgia: results of a controlled trial.

Deluze, C.; Bosia, L.; Zirbs, A.; Chantraine, A; Vischer, Thomas L.

doi:10.1136/bmj.305.6864.1249

Cited by 266 publications

(229 citation statements)

References 26 publications

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“…Four studies could be combined in an analysis regarding the immediate treatment effect [22,37,49,93], and two studies were analyzed regarding longterm effects of acupuncture in pain conditions [49,52]. The results of these metaanalyses confirm our descriptive findings.…”

Section: Meta-analysissupporting

confidence: 71%

“…Nine of these reported the PPT to be significantly elevated [33,40,41,43,51,64,78,79,83], and one study found no significant PPT increase [50]. Among the 26 studies (74.3%) that assessed the effectiveness of an acupuncture series, 18 (69.2%) showed a PPT increase after treatment [37,38,46,50,52,62,63,68,70,72,74,77,81,82,86,87,91,93] while six studies (23.1%) observed no effect of acupuncture on the PPT [22,27,[47][48][49]96]. The outcome of two studies was rated as unclear, because the analysis was performed by combining data of all groups [44,45].…”

Section: Ppt Assessed In Pain Disordersmentioning

confidence: 99%

“…2. Only six studies (7.1%) were rated as 'low risk of bias' in six or more items of the Cochrane risk of bias tool [33,37,40,47,49,62]. A judgment as 'high risk of bias' resulted most frequently from methodological shortcomings within the ''+'' indicates a change of the respective threshold through acupuncture, ''-'' indicates no effect of acupuncture, ''?''…”

Section: Quality Of Included Studiesmentioning

confidence: 99%

“…Most common conditions under investigation were myofascial pain, associated with the occurrence of MTrPs (8 out 35, 22.9%) [33,38,41,48,50,63,70,83], fibromyalgia (7 out of 35, 20%) [37,44,45,72,81,82,87], chronic neck and back pain (5 out of 35, 14.3%) [22,46,49,74,77], temporomandibular disorder (5 out of 35, 14.3%) [40,43,68,79,91], and experimentally induced delayed-onset muscle soreness (DOMS; 4 out of 35, 11.4%) [27,47,51,78]. PPT was also used as an outcome measure for the treatment effect of acupuncture in tension type headache [52,93], osteoarthritis of the knee [86], abdominal scar pain [62], plantar fasciitis [96], and syringomyelia [64].…”

Section: Ppt Assessed In Pain Disordersmentioning

confidence: 99%

“…In the following, the term ''sham'' is used according to the description of the respective publication. Sham interventions were needling at non-acupuncture points with stimulation (17 out of 48; 35.4%) [24, 25, 30, 31, 35, 42-44, 50, 53, 62, 73, 83-85, 94, 95], without or with minimal stimulation (10 out of 48; 20.8%) [22,27,37,44,46,47,57,86,93,95], minimal or no intensity needle stimulation at classical acupuncture points (10 out of 48; 20.8%) [40,44,66,80,88,92,95,97,103,104], non-penetrating placebo needles (12 out of 48; 25%) [28,33,45,52,60,61,72,76,78,79,98,99], or treatment with an inactive laser pen (5 out of 48; 10.4%) [31,48,49,77,95]. In 25 of these 48 studies (52.1%) the effect on sensory thresholds was significantly larger in the verum than in the sham acupuncture group [25, 28, 31, 33, 37, 40, 46, 50, 52, 57, 60, 62, 72, 76, 78-80, 83-85, 88, 92, 93, 95, 97].…”

Section: Comparison Of Verum Acupuncture To Inert or Sham-control Promentioning

confidence: 99%

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Effects of Acupuncture on Sensory Perception: A Systematic Review and Meta-Analysis

Baeumler¹,

Fleckenstein²,

Takayama

et al. 2015

Deutsche Zeitschrift für Akupunktur

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Background: The effect of acupuncture on sensory perception has never been systematically reviewed; although, studies on acupuncture mechanisms are frequently based on the idea that changes in sensory thresholds reflect its effect on the nervous system. Methods: Pubmed, EMBASE and Scopus were screened for studies investigating the effect of acupuncture on thermal or mechanical detection or pain thresholds in humans published in English or German. A meta-analysis of high quality studies was performed. Results: Out of 3007 identified articles 85 were included. Sixty five studies showed that acupuncture affects at least one sensory threshold. Most studies assessed the pressure pain threshold of which 80% reported an increase after acupuncture. Significant short-and long-term effects on the pressure pain threshold in pain patients were revealed by two meta-analyses including four and two high quality studies, respectively. In over 60% of studies, acupuncture reduced sensitivity to noxious thermal stimuli, but measuring methods might influence results. Few but consistent data indicate that acupuncture reduces pin-prick like pain but not mechanical detection. Results on thermal detection are heterogeneous. Sensory threshold changes were equally frequent reported after manual acupuncture as after electroacupuncture. Among 48 sham-controlled studies, 25 showed stronger effects on sensory thresholds through verum than through sham acupuncture, but in 9 studies significant threshold changes were also observed after sham acupuncture. Overall, there is a lack of high quality acupuncture studies applying comprehensive assessments of sensory perception.

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Section: Meta-analysissupporting

confidence: 71%

Section: Ppt Assessed In Pain Disordersmentioning

confidence: 99%

Section: Quality Of Included Studiesmentioning

confidence: 99%

Section: Ppt Assessed In Pain Disordersmentioning

confidence: 99%

Section: Comparison Of Verum Acupuncture To Inert or Sham-control Promentioning

confidence: 99%

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Effects of Acupuncture on Sensory Perception: A Systematic Review and Meta-Analysis

Baeumler¹,

Fleckenstein²,

Takayama

et al. 2015

Deutsche Zeitschrift für Akupunktur

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Fibromyalgia Syndrome a Decade Later

Goldenberg¹

1999

Arch Intern Med

188

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Management of Fibromyalgia Syndrome

Goldenberg¹

2004

JAMA

739

476

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T ANY ONE TIME, 10% TO 12% of the general population report chronic generalized musculoskeletal pain that cannot be traced to a specific structural or inflammatory cause. 1 Such idiopathic widespread pain most often will fit the classification criteria for fibromyalgia syndrome (FMS). 2 The diagnosis of FMS is based on a history of widespread pain, defined as bilateral, upper and lower body, as well as spine, and the presence of excessive tenderness on applying pressure to 11 of 18 specific muscle-tendon sites. 3 The 1990 American College of Rheumatology classification criteria for the diagnosis of fibromyalgia provide a sensitivity and specificity of nearly 85% in differentiating FMS from other forms of chronic musculoskeletal pain. Surveys using these criteria have found an FMS prevalence of 2% in the United States, including 3.4% of women and 0.5% of men. 4,5 Fibromyalgia is the second most common disorder observed by rheumatologists (after osteoarthritis), yet rheumatologists in the United States currently provide care for less than 20% of individuals with fibromyalgia. 6,7 Chronic pain syndromes, such as FMS, are defined by subjective symptoms and lack unique pathophysiological characteristics. Questions often arise regarding the nature and existence of illnesses like FMS. Indeed, no discrete boundary separates syndromes such as FMS, chronic fatigue syndrome, irritable bowel syndrome, or chronic muscular headaches. 8 Furthermore, these illnesses are each comorbid with mood disturbances. 9 Defining pain syndromes like FMS, headaches, or back pain provides a common framework to study the clinical and physiological characteristics. 10 Research during the past decade has demonstrated similar abnormal pain processing in FMS and related chronic pain syndromes. Patients with FMS have lowered mechanical and thermal pain thresholds, high pain ratings for noxious stimuli, and altered temporal summation of pain stimuli. 10-13 Physiological evidence of altered pain processing in FMS has been demonstrated by brain imaging 14-16 as well as CME available online at www.jama.com

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Electroacupuncture in fibromyalgia: results of a controlled trial.

Cited by 266 publications

References 26 publications

Effects of Acupuncture on Sensory Perception: A Systematic Review and Meta-Analysis

Effects of Acupuncture on Sensory Perception: A Systematic Review and Meta-Analysis

Fibromyalgia Syndrome a Decade Later

Management of Fibromyalgia Syndrome

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