BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality throughout the world. Pulmonary hypertension is the major cardiovascular complication of COPD; this is associated with right ventricular dysfunction and corpulmonale which has a poor prognosis. The detection of right ventricular (RV) hypertrophy in electrocardiography (ECG) has a high specificity but very low sensitivity. 2-D echocardiography can be used to assess right ventricular dimensions and the presence of pulmonary artery hypertension in patients with COPD. AIMS: This study was undertaken to observe the electrocardiographic and echocardiographic changes in COPD patients with different grades of severity as assessed clinically and through spirometry and correlate the findings with duration and severity of the disease. METHODS: 50 patients with COPD were randomly selected over a period of 2 years. All cases were studied clinically, and underwent chest X-ray, electrocardiography, echocardiography, and spirometry. The severity of the disease was graded according to BTS (British thoracic society) guidelines. Statistical analysis of correlation was done with Pearson's test and Chi square test, and statistical significance was taken a p < 0.05. RESULTS: Mean age was 59.9+/-10.4 years, with male preponderance. Mean duration of disease was 5.71 years, with mean exposure to smoking of 23.2 +/-3.6 pack years. ECG findings that showed significant correlation with severity of disease were 'p' pulmonale, right axis deviation, right bundle branch block, right ventricular hypertrophy and poor 'R' wave progression. Only right axis deviation increased significantly with duration of disease. Among echocardiographic findings, R.A (right atrial)/R.V dilatation, R.V. failure, pulmonary hypertension and corpulmonale also showed significant correlation with severity of disease. With respect to duration of disease, R.V. dilatation, pulmonary hypertension and corpulmonale showed significant increased occurrence with increasing duration of disease .Diagnosis of corpulmonale clinically was 36%, by ECG was 44% and by echocardiography was 54%. CONCLUSION: COPD is more common in males in 5 th to 7 th decade of life, with a smoking history of more than 20 pack years. Most patients have moderate to severe disease at presentation. The occurrence of ECG and echocardiographic findings increase as severity and duration of disease increases, and echocardiography detects more number of patients with R. V. dysfunction than ECG or clinical methods.