1970
DOI: 10.1136/bmj.2.5704.268
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Electrocardiographic Changes and Plasma Potassium Levels in Patients on Regular Haemodialysis

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Cited by 24 publications
(14 citation statements)
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“…Also, dialysis patients are reported to have a tolerance of hyperkalaemia, due to a relatively slow rate of increase in serum potassium compared to the general population, when an excess of potassium is ingested [17,30]. This goes some way to explain the absence of T-wave tenting where it may have been expected [8]. However, this study and others have noted normal ECGs despite the presence of a serum potassium of >9.0 mmol/L [15,44].…”
Section: Clinical Predictors Of T-wave Tentingcontrasting
confidence: 47%
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“…Also, dialysis patients are reported to have a tolerance of hyperkalaemia, due to a relatively slow rate of increase in serum potassium compared to the general population, when an excess of potassium is ingested [17,30]. This goes some way to explain the absence of T-wave tenting where it may have been expected [8]. However, this study and others have noted normal ECGs despite the presence of a serum potassium of >9.0 mmol/L [15,44].…”
Section: Clinical Predictors Of T-wave Tentingcontrasting
confidence: 47%
“…It is also responsible for at least 1.2% of deaths in dialysis patients in the USA [7], though the actual figure may be greater, given the high rate of sudden or unexpected death suffered by this population. The earliest electrocardiogram (ECG) abnormality of hyperkalaemia is classically the 'tented' or 'peaked' T-wave seen in the precordial leads [8,9]. This occurs because potassium channels are partly responsible for the repolarization phase of the cardiac action potential.…”
Section: Introductionmentioning
confidence: 99%
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“…This prediction was supported by the finding of positive BSPL values (recorded with 0.5% KCl) in subjects having particularly high-amplitude T-waves (CHRISTIE and VENABLES, 1971c). Such T-waves would be associated with high concentrations of plasma K+ (PAPADIMITRIOU et al, 1970) and therefore, we would argue, with high concentrations of K+ in the horny layer's intercellular fluid. Further, we would argue that such intercellular fluid represents the" [K]internal" of Eq.…”
Section: Resultssupporting
confidence: 68%
“…The measured SPL at a "basal" point (BSPL) was shown to have a significant inverse correlation (r=-0.7, P<0.001) with the amplitude of the electrocardiogram (ECG) T-wave. As this amplitude increases when KCl is ingested (MASHIMA et al, 1965) and is significantly correlated (r=0.68, P<0.001) with plasma potassium concentration ([K+]) (PAPADIMITRIOU et al, 1970), its significant inverse correlation with BSPL is taken as evidence for the importance of a nonsudorific factor related to extracellular fluid (ECF) [K+] in the generation of BSPL.…”
mentioning
confidence: 99%