In this work, the analytical use of facilitated ion transfer of catecholamines by dibenzo-18-crown-6 was investigated at the water/1,6-dichlorohexane interface using electrochemical methods (cyclic and square wave voltammetry). The experimental conditions for the analytical determination of noradrenaline and dopamine were established and detection limits of 1.7 and 0.35 mM were obtained, respectively. The effect of excess ascorbic acid on the transfer and detection of the two catecholamines was investigated. The selectivity coefficients obtained for dopamine and noradrenaline in the presence of ascorbic acid were 3.5 10 À4 and 2.5 10 À3 , respectively.