The synthesis and electrocatalytic performance of iridium-oxide (IrO 2 ) are reported. IrO 2 was electrochemically deposited on the gold dendrite template prepared by the chronoamperometry. The influence of the synthetic condition on the morphology, phase composition, and accessible surface area of the IrO 2 dendrites was investigated. The optimized IrO 2 dendrites showed an excellent electrocatalytic activity toward oxygen evolution with a low overpotential of 240 mV at 5 mAcm −2 and to the sensing of hydrogen peroxide with a high sensitivity of 692. The advantageous features of iridium oxide (IrO 2 ) include a high stability with exceptional resolution and corrosion resistances, reversible redox properties, and a sound biocompatibility for use in implantable devices. Due to these characteristic features, IrO 2 has been investigated for electrocatalytic applications such as water splitting, [1][2][3] pH sensing, 4,5 and amperometric biosensing; 6,7 however, its high cost and limited abundance require the most-efficient utilization of IrO 2 possible. 8,9 To enhance the electrocatalytic activity of IrO 2 at a low cost, IrO 2 catalyst is designed into a nanostructure. The structurally controlled IrO 2 catalyst can provide a large and accessible active surface area, and it facilitates electro-and mass transport. For these reasons, several researchers have developed the IrO 2 nanostructures in different ways. Electrodeposited IrO 2 nanoparticles for pH sensing were reported by Kim et al. 4 The preparation of IrO 2 nanofibers using electrospinning technique, and their application in ascorbic acid sensor electrode with binder was reported by Kim et al. 6 Sun et al. prepared IrO 2 nanorods using a CdSe/CdS/TiO 2 -nanorod template at 480• C. 10 With the use of a colloidal-SiO 2 template and heat-treatment, macroporous IrO 2 was prepared by Hu et al. 11 The reported IrO 2 structures were prepared via complex processes at high annealing temperatures or with the use of a template that required a multi-step preparation.As is well known, a dendrite structure, consisting of a main stem and numerous side branches, receives significant attention as a catalyst and other technological fields. The large surface area, short diffusion length, and sound mechanical integrity of the dendrite can provide both an extraordinarily high activated surface and a robust stability that are due to the micro-and nano-sized assemblies.12-15 To directly synthesize a metal dendrite on a conductive substrate, electrodeposition can be easily employed without any post-treatment at room temperature.Here, we introduce a simple method to achieve IrO 2 dendrite; the gold dendrite was prepared on titanium (Ti) foil using a facile electrodeposition (ED), and IrO 2 was then electrochemically deposited on the gold dendrite. There are only a few studies on the IrO 2 dendrite in the literature. The dendritic structure of IrO 2 was well controlled by the electrodeposition cycle number. An optimized IrO 2 electrode was applied to the electrocatalytic application f...