Electrochemical and Piezoelectric Enantioselective Sensors and Biosensors

Abstract

Enantioselectivity in chemical and biochemical sensing probes can be obtained by the use of enantioselective binding or by enantioselective biocatalysis. The enantioseletive discrimination in ion-selective electrodes can be achieved with the use of appropriate ionophore in plasticized membrane in measuring cell or on the surface of electrode, with the use of a suitable enzyme in biosensor, antibody in immunosensor, or molecularly imprinted polymer for modification of active surface of amperometric or voltammetric sensor. This review, based on 77 literature references mostly from 1992 to 2004, reports developments of such sensors for potentiometric, amperometric, and mass-detecting devices involving quartz crystal microbalances. for allowing MW to have study visits in their laboratories to get experimental experience in fabrication of potentiometric sensors and amperometric biosensors.

Effect of pH on the Enantiospecificity of Homocysteine Monolayer on Au(111) for the Redox Reaction of 3,4‐Dihydroxyphenylalanine

“…In addition, electrodes with enantiospecificity are expected to be useful not only as a chemical sensor of a specific enantiomer [2], but also for enantioselective synthesis and for enantioselective decomposition. For those applications, a high enantiospecificity is important, while enantiospecificity is more difficult to achieve than other molecular recognitions because the difference between enantiomers lies only in their structures.…”

Imprinted Polymers

“…Various electrochemical sensors and piezoelectric enantioselective sensors and biosensors are described in a review written by Trojanowicz and Wcislo [83]. This report covers the development of sensors for potentiometric, amperometric, and mass-detecting devices involving QCM.…”

An Ascorbic Acid Oxidase-based Sensing Platform for Stereoselective Interaction with Ascorbic Acid and Isoascorbic Acid

“…Therefore, stereoselective interaction plays an important role in biochemistry, pharmaceutics and other relevant fields. 3,4 Ascorbic acid (AA), commonly known as vitamin C, is a kind of natural antioxidant and cofactor of enzyme in biological systems. [5][6][7] Isoascorbic acid (IAA) as a common stereoisomer of AA is also legally used as an antioxidant food additive for its antioxidant property that is similar to that of AA.…”