Electrochemical and spectroscopic detection of insulin using AgNPs-decorated organic derivative

Bhardwaj, Geetika; Kaur, Randeep; Saini, Sanjeev; Kaur, Navneet; Singh, Narinder

doi:10.1016/j.colsurfa.2023.132511

Cited by 2 publications

(2 citation statements)

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“…The linear plot of the square root of the scan rate vs redox peak current represents the linearity due to the diffusioncontrolled process (Figure 4B inset). 45 Electrochemical Recognition. For the detection of DCP, the hybrid material modified electrode was optimized over the pH range 2−12.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

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Calix Decorated ZnO Nanohybrid Material Based Smart Portable Electrochemical Device for On-Site Analysis of Diethylchlorophosphate

Kaur,

Bhardwaj,

Singh

et al. 2024

ACS Appl. Nano Mater.

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Chemical warfare agents (CWAs) pose a severe threat to both civilians and military personnel due to their extreme toxicity. The urgent necessity of creating a portable device for rapid on-site quantification of CWAs is evident. This article presents the design and synthesis of a specialized material, calix[4]pyrrole R2 modified zinc oxide nanohybrid material (R2-ZnO), and its utilization in crafting a smart portable electrochemical device (SPED). The detection capability of the R2-ZnO nanohybrid material was evaluated using various electrochemical techniques, specifically targeting the identification of CWAs' mimic compound, diethyl chlorophosphate (DCP). Upon interaction with the R2-ZnO nanohybrid material, DCP gets entrapped within the pyrrolic cavity of the R2-ZnO nanohybrid material and transforms into hydrolyzed, nontoxic compounds, resulting in a significant increase in current intensity. The interaction of DCP with the R2-ZnO nanohybrid material generates a quick response by enhancing the remarkable current density of the material. Surprisingly, when the R2-ZnO nanohybrid material was exposed to other organophosphates, there was no observable change in the current. Additionally, the developed SPED was tailored for the quantification of DCP, demonstrating fast response times within seconds of exposure. This pioneering research offers a promising pathway to develop a cost-effective, portable device for the rapid on-site quantification of hazardous CWAs.

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Section: ■ Results and Discussionmentioning

confidence: 99%

“…Moreover, the scan rate studies of the R2-ZnO/ GCE hybrid material were performed in a 5 mM solution of [Fe(CN) 6 ] 3–/4– at different scan rates (20–220 mV/s) (Figure B). The linear plot of the square root of the scan rate vs redox peak current represents the linearity due to the diffusion-controlled process (Figure B inset) …”

Section: Resultsmentioning

confidence: 99%