2024
DOI: 10.1021/acs.langmuir.3c03263
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Electrochemical and Spectroscopic Studies Performed for Indomethacin and 1-Naphthol Incorporated in 1-Butyl-3-methyl-imidazolium Bis(2-ethylhexyl) Sulfosuccinate Vesicles to Investigate Them as a Potentially pH-Sensitive Nanocarrier

Luis F. Berrio Velasco,
Fernando Moyano,
Patricia G. Molina
et al.

Abstract: Characterization studies of 1-butyl-3-methyl-imidazolium bis(2-ethylhexyl) sulfosuccinate vesicles at different pH values have been carried out by using liquid surface tension, transmission electron microscopy, and dynamic light scattering. The results show that there are no vesicle changes in its size and negative Z potential at pH 3, 6, and 10. Furthermore, indomethacin and 1-naphthol, both pH-dependent, electroactive, and fluorescence probes, were used to further characterize the bilayer employing electroch… Show more

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“…Furthermore, the vesicular aggregates are influenced by the scattering of the solution, which may impede their respective analysis by these techniques. Therefore, as an alternative solution for the analysis of interactions between drugs and membranes, electrochemical techniques are proposed. , …”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, the vesicular aggregates are influenced by the scattering of the solution, which may impede their respective analysis by these techniques. Therefore, as an alternative solution for the analysis of interactions between drugs and membranes, electrochemical techniques are proposed. , …”
Section: Introductionmentioning
confidence: 99%