Electrochemical aptasensor based on bimetallic CuZr-MOF for ultrasensitive detection of miR-21

Gorgani, Leila; Mohammadi, Maedeh; Darzi, Ghasem Najafpour; Raoof, Jahan Bakhsh

doi:10.1016/j.snb.2022.133194

Cited by 26 publications

(5 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results exhibited that the aptasensor had a linear response to miR-21 concentrations from 1 zM to 1 pM, with a high correlation coefficient (R2) of 0.99. The lowest miR-21 concentrations that could be detected and quantified by the aptasensor were 0.45 and 1.5 zM, respectively, which demonstrates its high sensitivity and precision 140 .…”

Section: Aptamer-embedded Inorganic Nanomaterialsmentioning

confidence: 87%

Aptamer-engineered (nano)materials for theranostic applications

Rabiee,

Chen,

Ahmadi

et al. 2023

Theranostics

View full text Add to dashboard Cite

A diverse array of organic and inorganic materials, including nanomaterials, has been extensively employed in multifunctional biomedical applications. These applications encompass drug/gene delivery, tissue engineering, biosensors, photodynamic and photothermal therapy, and combinatorial sciences. Surface and bulk engineering of these materials, by incorporating biomolecules and aptamers, offers several advantages such as decreased cytotoxicity, improved stability, enhanced selectivity/sensitivity toward specific targets, and expanded multifunctional capabilities. In this comprehensive review, we specifically focus on aptamer-modified engineered materials for diverse biomedical applications. We delve into their mechanisms, advantages, and challenges, and provide an in-depth analysis of relevant literature references. This critical evaluation aims to enhance the scientific community's understanding of this field and inspire new ideas for future research endeavors.

show abstract

Section: Aptamer-embedded Inorganic Nanomaterialsmentioning

confidence: 87%

Aptamer-engineered (nano)materials for theranostic applications

Rabiee,

Chen,

Ahmadi

et al. 2023

Theranostics

View full text Add to dashboard Cite

show abstract

“…This is because they have functional groups, such as amines and carboxyls, and can be functionalized according to the application. Additionally, they are capable of generating π-stacking and hydrogen interaction with negatively charged aptamers [84].…”

Section: Nanomaterial-modified Electrochemical Aptasensorsmentioning

confidence: 99%

Relevant Aspects in the Development of Electrochemical Aptasensors for the Determination of Antibiotics—A Review

da Silva,

Pereira

2023

Electrochem

View full text Add to dashboard Cite

Aptamers are three-dimensional structures of DNA or RNA that present high affinity and selectivity to specific targets, obtained through in vitro screening. Aptamers are used as biological recognizers in electrochemical biosensors, the so-called aptasensors, providing greater specificity in recognizing the most diverse analytes. Electrochemical aptasensors have extremely relevant characteristics, such as high sensitivity, low cost compared to other biorecognizers such as antibodies, and excellent compatibility, being considered one of the most promising alternative methods in several areas, such as biomedical diagnosis and monitoring environmental contaminants. In this sense, the present work reviews the relevant aspects of methodologies based on electrochemical aptasensors and their applications in determining antibiotics, seeking to foster innovation in electrochemical biosensors.

show abstract

“…In addition, various nanomaterials, such as carbon nanomaterials (CNPs) (including carbon dots, graphene, and a series of derivatives, including carbon nanotubes, graphene oxide, and reduced graphene oxide) 4 and metal nanoparticle (MNPs) 5 complexes (a series of complexes including MOFs and MXenes), have been widely used in a variety of single-module biosensing fields by researchers due to their excellent sensing performance. For example, in the fields of disease diagnosis and monitoring, [6][7][8] there have been many excellent reviews on the application of these nanomaterials in the field of singlemodule biosensing for the measurement of trace pollutants in the environment [9][10][11] and to ensure food safety 12 and biosafety. 13,14 However, some of these nanomaterials have some limitations in practical application, which hinder their use as signal probes for multimodal biosensors.…”

Section: Introductionmentioning

confidence: 99%