Electrochemical behavior of esomeprazole: Its determination at Au electrode as standard and in injection powder combined with the study of its degradation

Ivić, Milka Avramov; Lović, Jelena; Stevanović, Sanja; Nikolić, Nebojša D.; Trišović, Nemanja; Lađarević, Jelena; Vuković, Dragan; Drmanić, Saša Ž.; Mladenović, Aleksandar; Jadranin, Milka; Petrović, Slobodan; Mijin, Dušan Ž.

doi:10.1016/j.jelechem.2019.113303

Cited by 9 publications

(5 citation statements)

References 33 publications

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“…Figure 2 presents CVs for the oxidation of sertraline and its inclusion complexes with HPβCD as well as the voltammogram of the Au electrode in the blank solution for the sake of comparison. The electrochemical behavior of Au was described by taking into account adsorption processes, such as chemisorption of OH − , which occurred in the potential region of -0.1 to + 0.3 V vs. SCE followed by the oxide formation at more positive potentials [33]. The onset potential for the oxidation of sertraline and its inclusion complex with HPβCD were correlated with formation of AuOH species.…”

Section: Resultsmentioning

confidence: 99%

Electrochemical determination of sertraline in pharmaceutical formulation and serum using a gold electrode in a pH 8.4 bicarbonate solution

et al. 2021

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The electrochemical characterization of sertraline at gold electrode was examined by cyclic voltammetry measurements (CV) in pH 8.4 bicarbonate buffer. Then Au electrode was evaluated for the quantitative determination of sertraline using square wave voltammetry (SWV). To enhance the sensitivity during the drug determination, (2-hydroxypropyl)-β-cyclodextrin (HPβCD) and β-cyclodextrin (βCD) inclusion complexes were employed. Using the proposed SWV technique, the anodic current peak was linear within a concentration range of 0.1-0.5 µM with a limit of detection (LOD) of 2.0 × 10 -8 M and a limit of quantification (LOQ) of 6.7 × 10 -8 M. In the case of inclusion complex of the sertraline with HPβCD, a good linearity range of 0.1-0.9 µM was obtained with a LOD of 2.6 × 10 -8 M and a LOQ of 8.8 × 10 -8 M. The gold electrode revealed the same linearity range for inclusion complex of the sertraline with βCD with a LOD and a LOQ being 2.6 × 10 -8 and 8.6 × 10 -8 M, respectively. Comparing the regression equations, it can be concluded that the sensitivity in the presence of inclusion complex can be up to 5 times higher. The applicability of the developed method was confirmed by the analysis of this drug in pharmaceutical formulation and in human serum spiked with sertraline standard. The comparison to HPLC method was successfully performed.

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Section: Resultsmentioning

confidence: 99%

Electrochemical determination of sertraline in pharmaceutical formulation and serum using a gold electrode in a pH 8.4 bicarbonate solution

et al. 2021

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“…The probable explanation of the observed phenomenon may be supported by the electrochemical gold oxidation in basic solutions to the corresponding oxide. This effect was mentioned for bare gold in solutions of sodium hydroxide [31] or sodium hydrocarbonate [32]. This peak would have been saved if gold particles were deposited on the substrate, for example, on nickel hydroxide [31].…”

Section: Photoelectrochemical Properties Of Tio2/fto and Au/tio2/fto ...mentioning

confidence: 99%

Laser-Induced Chemical Liquid-Phase Deposition Plasmonic Gold Nanoparticles on Porous TiO2 Film with Great Photoelectrochemical Performance

et al. 2021

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This paper considers the photoelectrochemical characteristics of a composite porous TiO2 thin film with deposited plasmonic gold nanoparticles. The deposition of gold nanoparticles was carried out by the laser-induced chemical liquid-phase deposition (LCLD) method. The structural characteristics of the composite have been studied; it has been shown that the porous TiO2 film has a lattice related to the tetragonal system and is in the anatase phase. Gold nanoparticles form on the surface of a porous TiO2 film. A complex of photoelectrochemical measurements was carried out. It was shown that the deposition of plasmonic gold nanoparticles led to a significant increase in the photocurrent density by ~820%. The proposed concept is aimed at testing the method of forming a uniform layer of plasmonic gold nanoparticles on a porous TiO2 film, studying their photocatalytic properties for further scaling, and obtaining large area Au/TiO2/FTO photoelectrodes, including in the roll-to-roll process.

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“…Au electrode was mechanically polished on diamond paste, washed in mixture (50 % sulphuric acid, 50 % water) and washed with deionized water. 20 GC electrode was prepared by mechanical treatment, which involves abrasion with emery paper, polishing with Al 2 O 3 suspension (particle size 1, 0.3 and 0.05 µm), washed in mixture 50 % sulphuric acid/50 % water and washed with deionized water. Both electrodes were then electrochemically treated.…”

Section: Electrochemical Stability Of Metformin 1321mentioning

confidence: 99%

Electrochemical stability of metformin in NaHCO3 and Na2SO4 water solution at Au, GC and IrOx electrodes

Lović

Lađarević

Mijin

et al. 2019

JSCS

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In this study the electrochemical behavior of metformin (MET), oral antihyperglycaemic agent, was assayed at three different electrodes. The drug standard was investigated by cyclic voltammetry and square wave voltammetry via its electrooxidation at Au and glassy carbon electrode in 0.05 M NaHCO 3. Under these conditions transformation of MET to corresponding N-carbonyl guanidine via oxime intermediate is suggested. The stability of MET was tested under directed stress conditions using IrOx electrode with sodium sulphate as an electrolyte and cyclic 4-amino-2-imino-1-methyl-1,2-dihydro-1,3,5-triazine appeared as the main end-product. The courses of the electrochemical processes at three electrodes were followed by UV spectroscopy and evaluated by total organic carbon analysis.

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Electrochemical behavior of esomeprazole: Its determination at Au electrode as standard and in injection powder combined with the study of its degradation

Cited by 9 publications

References 33 publications

Electrochemical determination of sertraline in pharmaceutical formulation and serum using a gold electrode in a pH 8.4 bicarbonate solution

Electrochemical determination of sertraline in pharmaceutical formulation and serum using a gold electrode in a pH 8.4 bicarbonate solution

Laser-Induced Chemical Liquid-Phase Deposition Plasmonic Gold Nanoparticles on Porous TiO2 Film with Great Photoelectrochemical Performance

Electrochemical stability of metformin in NaHCO3 and Na2SO4 water solution at Au, GC and IrOx electrodes

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