2024
DOI: 10.1021/acsabm.4c00186
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Electrochemical Behavior of Janus Kinase Inhibitor Ruxolitinib at a Taurine-Electropolymerized Carbon Paste Electrode: Insights into Sensing Mechanisms

Hasret Subak,
Pınar Talay Pınar

Abstract: Ruxolitinib (RXL) is a Janus kinase inhibitor used for treating intermediate- or high-risk myelofibrosis. This study presents an electrode modified with electrochemically polymerized taurine on a carbon paste electrode via cyclic voltammetry (CV). The surface characterization of the poly(taurine)-CP electrode was evaluated by using electrochemical (electrochemical impedance spectroscopyEIS, CV), morphological (scanning electron microscopeSEM), and spectroscopic (Fourier-transform infrared spectroscopyFT-IR)… Show more

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