Electrochemical behaviour of 2-hydroxybenzophenones and related molecules

Copper-2-Hydroxyphenone CVs

“…Scheme 1. Naming, numbering, and structure benzophenones (1-9) and copper-2-hydroxyphenone complexes (10)(11)(12)(13)(14)(15)(16)(17)(18)(19). Scheme 1.…”

“…A fourth article mentioned the reduction potential of benzophenone and two para-substituted benzophenones [5]. While comprehensive electrochemical data on hydroxybenzophenones are available [18][19][20], no comprehensive scan rate study on the redox behaviour of benzophenone or other substituted benzophenones could be found in the literature, except that for benzophenone and 2-amino-5-nitrobenzophenone reported in the related research article [7]. Due to limited reported scan rate studies on substituted benzophenones, in this article, we provide CVs and electrochemical data describing the chemical and electrochemical reversibility of the benzophenone/[benzophenone • ] − redox couple.…”

“…Molecules containing electron-donating groups and ligands are oxidised at a lower potential than molecules containing electron-withdrawing groups and ligands. The influence of different electron donating and electron withdrawing groups on the reduction potential of structure benzophenones (1-9) and copper-2-hydroxyphenone complexes (10)(11)(12)(13)(14)(15)(16)(17)(18)(19) are shown in Figure 1 and Figure 2, respectively. This trend is as expected and in agreement with the trends observed for the reduction of enolised 1,3-diketones [30], parasubstituted nitrobenzenes [31], bis(cyclopentadienyl)mono(β-diketonato) titanium(IV) complexes [32,33], tris(β-diketonato)metal(III) complexes (metal = Co [34], Cr [35], Mn [36], and Fe [37]), and octahedral bis(β-diketonato)-titanium(IV) complexes [38].…”

“…The amount of shift to lower (due to electron-donating substituents) or higher (due to electronwithdrawing substituents) potentials, however, depends on the resonance and inductive electronic effects of the substituents [31,39]. (10)(11)(12)(13)(14)(15)(16)(17)(18)(19) containing electrondonating (OEt, OCH3) and electron withdrawing (Cl, Br) groups, relative to the copper-2-hydroxybenzophenone containing unsubstituted 2-hydroxybenzophenone (14). Data were obtained at a scan rate of 0.100 V s −1 in dimethyl sulfoxide as solvent from the related research article [8]. )…”

New mixed‐ligand iron(III) complexes containing thiocarbohydrazones: Preparation, characterization, and chemical reactivity analysis through theoretical calculations

“…[6][7][8] These compounds have a wide range of biological activities such as anticancer, anti-HIV, antimicrobial, anti-inflammatory, antioxidant and antitubulin activities. [9] Some benzophenone derivatives have been shown to be highly effective against wildtype HIV 1 and its reverse transcriptase. [10,11] Thiocarbohydrazones are an important class of compounds in the medical and pharmaceutical fields.…”