Electrochemical Benzylic C–H Amination via N-Aminopyridinium

Abstract

An electrochemical protocol for benzylic C(sp 3 )−H aminopyridylation via direct C−H/N−H cross-coupling of alkylarenes with N-aminopyridinium triflate has been developed. This method features excellent site-selectivity, broad substrate scope, redox reagent-free and facile scalability. The generated benzylaminopyridiniums can be readily converted to benzylamines via electroreductive N−N bond cleavage.