Electrochemical dehydroxymethylative functionalization of alkanols for forging C(sp³)–heteroatom bonds

Abstract

The construction of C(sp3)−heteroatom bonds represents a fundamental research field in synthetic chemistry. We report herein an electrochemical dehydroxymethylative functionalization reaction of aliphatic alcohols under mild and catalyst-free conditions, representing...

Electrochemical Deconstructive and Ring-Expansion Functionalization of Unstrained Cycloalkanols

“…Combined with relevant mechanistic experiments and the reported literature, ,,, we proposed a feasible mechanism for this electrochemical reaction, as depicted in Scheme . First of all, the cycloalkanol substrates ( a ) were oxidized at the anode to form alkoxy radicals I , followed by the β-scission process to form alkyl radicals II .…”