Electrochemical detection of bupropion drug using nanocomposite of molecularly imprinted polyaniline/Au nanoparticles/graphene oxide

A highly sensitive impedimetric sensor based on a MIP biomimetic for the detection of enrofloxacin

“…The increased electroactive surface area and conductivity of MIP films explain the excellent sensitivity of mAb-MIP based sensors. 26,40 Furthermore, both sensors' linear coefficients are low, at 0.9782 and 0.9813, respectively. Meanwhile, the detection limits of the two sensors were higher than those of the MIP sensor.…”

Electrochemical sensing platform based on screen-printed carbon electrode modified with plasma polymerized acrylonitrile nanofilms for determination of bupropion

“…The GCE [ 15 ] shows similar analytical parameters in terms of BUP determination as the mass-produced pp-AN/SPCE, but it is expensive and cannot be adopted in complex measurement systems (e.g., flow-through) offered by Methrom. Admittedly, the use of EIS technique allows to obtain very low LOD [ 16 ]; however, it also requires expensive equipment and the ability to use specialized software as well as many years of experience in interpreting EIS spectra. Importantly, the developed method is the first published so far, which is based on the electrooxidation of the secondary amine group of BUP.…”

“…Mainly chromatographic and spectrometric methods have been developed for BUP determination in pharmaceutical and biological samples, i.e., high-performance liquid chromatography with a spectrofluorometric detection [ 10 ], liquid chromatography coupled with tandem mass spectrometry [ 11 ], or capillary electrophoresis combined with phosphorescence detection [ 12 ]. In the case of electroanalytical methods, only a few examples of electrochemical sensors enabling the determination of BUP have been reported so far, including ion-selective PCV membrane electrodes [ 13 ], dropping mercury electrode [ 14 ], bulk glassy carbon electrode [ 15 ], and a carbon screen-printed electrode modified with molecularly imprinted polymer, gold nanoparticles, and graphene oxide as an electrochemical impedance spectroscopy sensor [ 16 ].…”