Electrochemical detection of paracetamol and dopamine molecules using nano-particles of cobalt ferrite and manganese ferrite modified with graphite

Abstract

Some electrodes for efficient detection of paracetamol and dopamine were developed from nano sized material of cobalt ferrite (np-CoFe 2 O 4 ) and manganese ferrite (np-MnFe 2 O 4 ). These oxides were synthesized by combustion method using cobalt nitrate, manganese acetate and ferric nitrate as precursors in the presence of sugar and ethanolamine. The crystallite size, shape and morphology of nano material were characterized by X-ray diffraction pattern (XRD), field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray spectroscopy (EDS) techniques. The crystallite sizes of synthesized nano-particles (nps) were in the range from 10 to 12 nm (calculated using Debye-Scherrer equation) with cubic crystal system. These particles were utilized as electrode modified with graphite for simultaneous detection of paracetamol and dopamine through cyclic voltammetry and Differential pulse voltammetry techniques and was found to be superior to reported literatures. The minimum detection limit of paracetamol and dopamine at CoFe 2 O 4 /GP electrode were 250 nM and 350 nM while at MnFe 2 O 4 /GP electrode it was 300 nM and 400 nM, respectively. Both the electrodes exhibited the linearity range from3 μM to 200 μM & 3 μM–160 μM for paracetamol and 3 μM–180 μM & 5 μM to 200 for dopamine, respectively. Two oxidation peaks of paracetamol and dopamine were well separated in phosphate buffer (pH = 6) in mixture with 100 mVs -1 and 50 mVs -1 scan rate for cyclic voltammetry and Differential pulse voltammetry, respectively. Both the electrodes demonstrated satisfactory results in real samples of paracetamol and dopamine.

Electroactive Core–Shell Chitosan-Coated Lanthanum Iron Oxide as a Food Freshness Level Indicator for Tyramine Content Determination

“…The presence of the nano-ranged LFO provided a large number of active redox sites for the charge transportation, requisite for the electrocatalytic oxidation of tyramine. Additionally, such types of semiconductor materials possess numerous surface defects, which may also facilitate the charge transportation . On the other side, the existence of CS enhanced the electrostatic interactions of tyramine onto the modified electrode, thus offering higher sensibility.…”

“…Additionally, such types of semiconductor materials possess numerous surface defects, which may also facilitate the charge transportation. 31 On the other side, the existence of CS enhanced the electrostatic interactions of tyramine onto the modified electrode, thus offering higher sensibility. The presence of −NH 2 and −OH functionalities in the CS structure can facilitate the binding with the targeted analyte.…”

Core‐shell Hierarchical Enzymatic Biosensor Based on Hyaluronic Acid Capped Copper Ferrite Nanoparticles for Determination of Endocrine‐disrupting Bisphenol A

“…Ferrites are often used as versatile gas detection materials, offering high sensitivity, selectivity and long‐term stability [61]. Although ferrite structures have been used as one of the components of various composite systems for the detection of analytes such as dopamine [62], pesticides [63], paracetamol [64] in recent years sensor designs containing BPA very few ferrite structures are encountered. As seen in Table 1, these structures generally didn't contain any modification process on their surfaces and they were not enzymatic systems [11,31b, 57].…”

Reduced Graphene Oxide Carbon Yarn Electrodes for Drug Sensing

“…Figure 4A shows cyclic voltammograms of rGO-coated fibre electrodes in aqueous solutions containing potassium ferricyanide (10 mM) and KCl (0.1 M) at a scan rate of 100 mV s −1 . The rGO fibre electrodes (20 CV scans) give larger oxidation peak currents compared to bare carbon fibre electrodes that are shifted to a lower peak potential which indicate faster electron transfer kinetics and improved electrochemical properties (Kumar et al, 2019). Electrochemical surface area (ECSA) measurements were performed the on PPy-rGO coated carbon fibre and Figure 4B shows cyclic voltammograms of PPy-rGO fibre electrodes in aqueous solutions containing potassium ferricyanide.…”