“…Therefore, electrochemical methods, such as voltammetry, have been adopted for the trace detection of fluoroquinolone antibiotics. – However, the bare electrodes usually suffer from a poor sensitivity toward LEV due to the sluggish electron-transfer process . To address this issue, electrocatalysts based on noble metal nanoparticles (NPs), – conducting polymers, – metal–organic frameworks (MOFs), , graphene, and graphene derivatives – have been used to modify glassy carbon electrodes (GCEs) to promote electron transfer and enhance the sensitivity. However, noble metal NPs are expensive and tend to oxidize and aggregate at room temperature.…”
The excessive use of levofloxacin (LEV) can lead to significant environmental pollution, while also damaging human health. The accurate detection of its concentration is therefore essential to protect both the environment and human health. Herein, we report the simple synthesis of α-zirconium phosphate supported on nitrogen-doped graphene nanosheets (α-ZrP/NG) and its application in the voltammetric determination of trace LEV in real samples. The surface morphology, microstructure, and electrochemical properties of α-ZrP/NG were investigated by microscopic and spectroscopic techniques. The analytical parameters, including the accumulation potential, accumulation time, loading volume, and buffer pH, were optimized to improve the electrocatalytic sensing performance of α-ZrP/NG. Owing to the synergetic interaction between α-ZrP and NG, the proposed sensor exhibited an excellent electrocatalytic activity for the electrical oxidation of LEV. In the range of 0.01−5.0 μM, the anodic peak current of LEV increased linearly with an increase in the LEV concentration, and the limit of detection was 2.6 nmol L −1 . Finally, the LEV levels in wastewater, human serum, milk, and eye drop samples were determined by using the α-ZrP/NG system combined with a glassy carbon electrode to give satisfactory recoveries (98.48−103.2%), indicating that the prepared sensor demonstrates promise for use in environmental, food, and drug monitoring applications.
“…Recently, Zhou et al proposed a Cu-MOF derivative (synthesized by Cu(CH 3 COO) 2 , CMC powder, and C 6 H 8 O 7 ) modified with a screen-printed electrode (SPE) for the detection of levofloxacin (LEV) via a electrochemical method with significant selectivity and stability . Due to existence of largely dispersed active sites, a high specific surface area in the MOF derivative, Cu-MOF derivative/SPE enabled full contact with LEV.…”
Section: Electrochemical Sensing Of Environmental Pollutantsmentioning
confidence: 99%
“…modified with a screen-printed electrode (SPE) for the detection of levofloxacin (LEV) via a electrochemical method with significant selectivity and stability. 107 Due to existence of largely dispersed active sites, a high specific surface area in the MOF derivative, Cu-MOF derivative/SPE enabled full contact with LEV. In cyclic voltammetry, LEV was evaluated in the potential range of −0.2 to 1 V with a linear concentration range of 0.1−100 μM and an LOD value of 0.016 μM, whereas LODs were 0.17 μM and 0.037 μM for DPV and chronoamperometry methods, respectively.…”
Environmental contamination has been a notorious danger to mankind. Fast development, modern industrialization, change in lifestyle of the masses, and incomplete knowledge about material safety data sheets (MSDS) of every material/chemical discharged cause degradation of the environment. To monitor and control of such pollution, there is an urgent requirement for innovative methods for identification, classification, and quantification of the pollutants with excellent performance (like high selectivity, high sensitivity, fast response time, and reliability). Among several analytical sensing techniques, an electrochemical method of detection, using metal−organic frameworks (MOFs) as the sensing platform for trace quantity recognition of ecological analytes, grabs most of the attention due to its very high sensitivity, nonspecific way of measurement (absorption/fluorescence are very specific), both redox noninnocent and innocent analytes could be determined, quick response time, use of single instrument for different measurements, etc. MOFs are porous coordination polymers (CPs) formed by coordination of metal nodes/clusters and multitopic organic linkers as ligands. Due to their large surface area, permanent porosity, abundant microcrystalline structures and ease of the tailoring, postsynthetic modification properties of MOFs have made them advantageous for storage, catalysis, sensing, separation, and biological applications. On combining with small biomolecules, organic dyes, nanoparticles, nanowires, nanofibers, etc., composite MOFs have better mechanical stability, catalytic performance, conductivity, and sensing application. This review is focused on the recent attention of the electrochemical sensing applications of MOFs and their composites. Electrochemical sensors are an economical and suitable technique for the detection of different analytes and are extensively utilized in agriculture, food, oil, dyes and pigments, pharmaceutical industries, and biomedical applications. Herein, we have highlighted the use of MOFs in the sensing of different environmental contaminants i.e., volatile organic compounds (VOCs), phenolic compounds, heavy metal ions, antibiotics, pesticides, hydrazine, nitrite, nitroaromatic compounds, etc. This Review covers the publications from 2000 to 2024 (January), and we are confident that this review will enable new inspiration to exploit MOFs-based advanced electrochemical sensing properties in the future.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
