Electrochemical determination of melatonin hormone using a boron-doped diamond electrode

Levent, Abdulkadir

doi:10.1016/j.diamond.2011.10.018

Cited by 80 publications

(50 citation statements)

References 45 publications

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“…10 Voltammetric and amperometric methods were applied for the determination of melatonin using carbon paste electrodes, carbon disk electrode, carbon fiber microdisk electrode, etc. [11][12][13] However, the electrochemical performance of carbon electrodes can be enhanced and/or extended by modifying their surfaces with various materials. One class of these materials are nanostructured carbonaceous materials, such as mesoporous carbon, carbon nanofibers, carbon nanotubes, and graphene.…”

Section: Introductionmentioning

confidence: 99%

Voltammetric determination of melatonin using a graphene-based sensor in pharmaceutical products

Apetrei

2016

IJN

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Melatonin can be sensitively detected in pharmaceuticals by cyclic voltammetry and fixed-potential amperometry using a graphene-based sensor. The sensor characterization of cyclic voltammetry constantly provides high values of electrode active area and heterogeneous rate constant. In optimal conditions, the sensor was applied for the determination of melatonin in different pharmaceutical samples. The sensitivity to melatonin was 0.0371 A M −1 , and the limit of detection was 0.87×10 −6 M. The data obtained by using the graphene-based sensor for the detection of melatonin in pharmaceutical products were in good agreement with the data provided by the producer. Since no interferences from the excipients were found, using a separation technique was not necessary. Additionally, the low price, ease of handling, small amount of sample, short time per analysis, and possibility of automation are the important advantages that recommend this methodology for quality control of pharmaceuticals.

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Section: Introductionmentioning

confidence: 99%

Voltammetric determination of melatonin using a graphene-based sensor in pharmaceutical products

Apetrei

2016

IJN

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“…The relative standard deviation (RSD) of each calibration experiments was less than 10% indicating acceptable reproducibility. Although it seems that this LOD is not as low as some other recent reports such as the LOD of 0.02µM (0.005 µg/ml) by CV measurement with multi-walled carbon nanotube (MWCNT) modified glassy carbon electrode [9], the LOD of 0.1µM (0.025 µg/ml) by square wave voltammetry (SWV) with boron-doped diamond microelectrode [10], and the LOD of 0.004µM (0.001µg/ml) by DPV oncarbon ionic liquid electrode modified with MWCNT and cobalt hydroxide nanoparticles [11], but the ease of preparation and a facile operation for ready use with considerable lower cost in comparable to satisfactory detection range for the onsite practical use has made the SPCEChi-CeO2 enduring attraction.…”

Section: Quantitative Determination Of Melatoninmentioning

confidence: 59%

Characterization of Cerium Oxide-Chitosan Nanocomposite–modified Screen Printed Carbon Electrode and Application in Melatonin Determination

Sunon

Wongkaew

Johns

et al. 2018

GEOMATE

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A simple and effective modification of the working screen printed carbon electrode (SPCE) surface has been developed with a mixture of chitosan biopolymer and nano cerium oxide at 1:1 composition for the detection of melatonin, a circadian rhythm regulation hormone. The fabricated electrode was characterized by scanning electron microscopy (SEM), energy dispersive X-ray spectrophotometer (EDS), electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). Electro-oxidation behaviors of melatonin were extensively observed by differential pulse voltammetric(DPV) analysis. The experimental results demonstrated that the modified cerium oxide-chitosan screen printed carbon electrode (SPCE-ChiCeO2) exhibited satisfactorily improvement in the electrochemical current sensitivity.Alinear calibration curve for melatonin was obtained in the concentration range from 0-10 µg/ml with a detection limit of 0.18 µg/ml based on DPV measurement. Good selectivity was also obtained in an interference study with some other closely structural related compounds such as tryptophan and serotonin. Thus this modification strategy was proved to be a suitable tool for the simple, fast, sensitive and selective determination of melatonin.

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“…In contrast, electrochemical techniques possess analytical and economic advantages including simple instrumentation and low-cost, high sensitivity, fast response and easy operation. In this way, it is important to point out that MT has not extensively been studied using electroanalytical approaches [20][21][22][23][24] and rarely the simultaneous detection of both 5-HT and MT molecules has been explored [21]. This relevant bibliography is also supported by recent reviews which have shown the significance of the nanomaterial-based approaches for electrochemical sensing of biogenic amines [25] and neurological drugs and neurotransmitters [26].…”

Section: Introductionmentioning

confidence: 94%

“…Consequently, the diffusion coefficient could be calculated for the electroactive molecule following Eq. 1, in which F is the Faraday constant, R is the gases constant, T is the temperature (298 K), n, is the number of transferred electrons (that is, 2) [23]; A, area of the electrodic surface (that is the geometric area of a CSPE, 0.0126 cm 2 ), D is the diffusion coefficient and c is the concentration of the electroactive specie.…”

Section: Electrochemical Proceduresmentioning

confidence: 99%

Screen-printed electrodes modified with carbon nanotubes or graphene for simultaneous determination of melatonin and serotonin

et al. 2015

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Single-walled carbon nanotubes (SWCNT), multiwalled carbon nanotubes (MWCNT) and graphene have been tested as carbon allotropes for the modification of carbon screen-printed electrodes (CSPEs) to simultaneously determine melatonin (MT) and serotonin (5-HT). Two groups of CSPEs, both 4 mm in diameter, were explored: The first includes commercial SWCNT, MWCNT and graphene, the second includes SWCNT, MWCNT, graphene oxide nanoribbons and reduced nanoribbons that were drop casted on the electrodes. The carbon nanomaterials enhanced the electroactive area in the following order: CSPE

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Electrochemical determination of melatonin hormone using a boron-doped diamond electrode

Cited by 80 publications

References 45 publications

Voltammetric determination of melatonin using a graphene-based sensor in pharmaceutical products

Voltammetric determination of melatonin using a graphene-based sensor in pharmaceutical products

Characterization of Cerium Oxide-Chitosan Nanocomposite–modified Screen Printed Carbon Electrode and Application in Melatonin Determination

Screen-printed electrodes modified with carbon nanotubes or graphene for simultaneous determination of melatonin and serotonin

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