Electrochemical Dopamine Detection using a Fe/Fe3O4@C Composite derived from a Metal‐Organic Framework

Abstract

In this paper, a novel composite of Fe/Fe 3 O 4 @C is synthesized by taking a Fe-metal-organic framework (Fe-MOF) as precursor template. Different treating temperature (450, 550, 650 and 750 °C) were carried out to investigate the composite of calcined products. The Fe/Fe 3 O 4 @C -650 modified glassy carbon electrode (Fe/Fe 3 O 4 @C -650 GCE) shows good electrocatalytic activity towards dopamine (DA) oxidation. Three electrochemical measuring methods of cyclic voltammetry (CV), differential pulse voltammetry (DPV) and amperometry i-t are adopted to investigate the sensing behaviors of Fe/Fe 3 O 4 @C -650 /GCE. The results show that: the sensors based on CV and DPV technology exhibit excellent advantages in the aspect of sensitivity and linear range thanthose of the sensor based on amperometry i-t technology. Meanwhile, the sensor based on CV method shows good selectivity for dopamine, and can resist the influence of various sugars, uric acid, ascorbic acid, as well as Na + and K + . The sensor also shows good stability and repeatability in the sensing process. In addition, the Fe/Fe 3 O 4 @C -650 /GCE could be successfully applied in the DA detection in the human serum.

Controllable synthesis of Pt nanoparticles on graphene oxide nanosheets and its application for electrochemical determination of dopamine

“…Varieties of strategies were designed based on abundant nanoparticles (single/multi‐ metals, metal oxides, metal sulfides, etc.) for fabrication electrochemical sensors [1–5] . According to the previous results, [6–8] the shape has a larger proportion than size in determining the catalytic activity of metal nanoparticles.…”

“…for fabrication electrochemical sensors. [1][2][3][4][5] According to the previous results, [6][7][8] the shape has a larger proportion than size in determining the catalytic activity of metal nanoparticles. Metallic nanocrystals have been prepared in a variety of different shapes for acquiring sensitivity sensors.…”

“…A variety of analytical techniques have been reported for different objective molecule analysis and detection. [25][26][27][28] Among these developed analytical techniques, electrochemical method was widely adopted owing to their advantages such as nontoxic, simplicity, low cost, rapid response, high sensitivity and high selectivity. [29][30][31] In order to avoid the higher overpotential during the electrooxidation DA process, many electrocatalytic nanomaterials based on the electrochemical proper-ties of DA were explored.…”

“…Sensitive and accurate determination of DA is of great significance in the filed of pharmacology and clinical medicine. A variety of analytical techniques have been reported for different objective molecule analysis and detection [25–28] . Among these developed analytical techniques, electrochemical method was widely adopted owing to their advantages such as nontoxic, simplicity, low cost, rapid response, high sensitivity and high selectivity [29–31] .…”

A Systemic Investigation on the Sensing Behaviors for Dopamine Based on the Combination of Cu-MOF and Various Carbon Materials

“…22 Thus, it is significance to devise an efficient DA detection means. 23,24 So far, there have been some reports on the detection of dopamine on the basis of composites composed by different MOFs and carbon materials as electrode materials. 25,26 For example, Lu and his colleagues also reported that Co 3 O 4 /FeCo 2 O 4 modified glassy carbon electrode for dopamine detection could detect the concentration of dopamine in the range of 0.1-250 μM with high sensitivity (0.04587 μM).…”