Electrochemical Generation of Steady-State Linear Concentration Gradients within Microfluidic Channels Perpendicular to the Flow Field

Abstract

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Lab-on-a-chip: an advanced technology for the modernization of traditional Chinese medicine

“…These channels divide the input flow into smaller segments, which were subsequently chaotically reorganized [ 81 ]. Beyond biomedical applications, multi-stream flow could also be used in advanced materials and sensing, such as the formation of particles with varying complexity and heterogeneity [ 82 , 83 ]. These instances underscored the sophisticated nature of microfluidic chips, emphasizing the necessity for researchers to design chip structures according to their research objectives and leverage unique fluidic effects to their fullest potential.…”

Optimization of Microbial a Fuel Cell with Linear Sweep Voltammetry and Microfluidics

“…On the other hand, analysis of Rohm+Rdiff in the diffusion-limited region showed continuous reductions from 35 to 22 kΩ while the flow rate ranged from 0.6 mL h -1 to 20 mL h -1 . As Rohm is roughly constant in this range, we attribute all changes in Rohm+Rdiff at high current densities to Rdiff, which decreases with flow-induced reductions of the boundary layer thickness [46][47][48]. At 30 mL h -1 , Rohm+Rdiff experienced a jump to approximately 45 kΩ, which we attribute to flow instability and a wandering co-flow interface.…”

Recent Advances in Microfluidic Technology for Bioanalysis and Diagnostics

“…Recently, Perrodin et al designed a microelectrode to form steady-state linear proton gradients perpendicular to the fluid stream in a microfluidic channel. Thus, parallel streams, splitting steps, and precise control of the microfluidic circuit are not required …”

“…Thus, parallel streams, splitting steps, and precise control of the microfluidic circuit are not required. 58 Mixing. Since microfluidic chips exhibit laminar flow profiles, the mixing of substances relies on molecular diffusion in passive mixing devices.…”