Electrochemical investigation of the voltammetric determination of hydrochlorothiazide using a nickel hydroxide modified nickel electrode

Machini, Wesley B. S.; David-Parra, Diego N.; Teixeira, Marcos F.S.

doi:10.1016/j.msec.2015.07.035

Cited by 30 publications

(9 citation statements)

References 42 publications

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“…[14,15] This electroanalytical technique hascertainadvantages with respect to other analytical techniques, such as ah igher speed, lower cost, and the generation of fewerr esidues. [16][17][18] In particular, SWV has some well-established advantages with respect to cyclic voltammetry (CV), for example, discrimination against background current and lower detection limits. [19,20] Therefore, SWV presentsa na ttractive technique for quantifying the concentration of electroactive drugs in different delivery systems.…”

Section: Introductionmentioning

confidence: 99%

“…Among these techniques, square wave voltammetry (SWV) has been used to study the behavior of confined electroactive molecules with high sensitivity in various systems . This electroanalytical technique has certain advantages with respect to other analytical techniques, such as a higher speed, lower cost, and the generation of fewer residues . In particular, SWV has some well‐established advantages with respect to cyclic voltammetry (CV), for example, discrimination against background current and lower detection limits .…”

Section: Introductionmentioning

confidence: 99%

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Square Wave Voltammetry: An Alternative Technique to Determinate Piroxicam Release Profiles from Nanostructured Lipid Carriers

et al. 2016

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A new, simple, and fast electrochemical (EC) method has been developed to determine the release profile of piroxicam, a nonsteroidal anti-inflammatory drug, loaded in a drug delivery system based on nanostructured lipid carriers (NLCs). For the first time, the samples were analyzed by using square wave voltammetry, a sensitive EC technique. The piroxicam EC responses allow us to propose a model that explains the experimental results and to subsequently determine the amount of drug loaded into the NLCs formulation as a function of time. In vitro drug release studies showed prolonged drug release (up to 5 days), releasing 60 % of the incorporated drug. The proposed method is a promising and stable alternative for the study of different drug delivery systems.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Square Wave Voltammetry: An Alternative Technique to Determinate Piroxicam Release Profiles from Nanostructured Lipid Carriers

et al. 2016

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“…The first was between 1.0 × 10 −7 and 5.0 × 10 −6 mol L Table 1 provides a comparison of the figures of merit of the proposed method and other techniques reported in the literature. The proposed sensor presented a lower limit of detection, compared to the values found elsewhere [15,17,34,37]. Although a lower limit of detection and higher linear range was obtained for the method described by Nezhadali [38], the novelty of the proposed sensor is that it enabled simultaneous determination of the analytes.…”

Section: Analytical Performancementioning

confidence: 72%

Adsorptive stripping voltammetry for simultaneous determination of hydrochlorothiazide and triamterene in hemodialysis samples using a multi-walled carbon nanotube-modified glassy carbon electrode

Hudari

Souza

Zanoni

2018

Talanta

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Hemodialysis is the most commonly used method for the treatment of chronic kidney disease. In this procedure, some patients use diuretics to control weight gain and blood pressure. In this work, a voltammetric sensor based on a glassy carbon electrode modified with carbon nanotubes (GCE/MWCNT) is described for the simultaneous determination of the diuretics hydrochlorothiazide (HCT) and triamterene (TRT). The oxidation of the diuretics on the GCE/MWCNT surface was observed at 1.01 and 1.17V for HCT and TRT, respectively, allowing simultaneous determination, which was not possible with the unmodified glassy carbon electrode. The GCE/MWCNT electrode provided 6-fold and 10-fold gains in anode peak intensity for HCT and TRT, respectively, compared to the unmodified electrode. After optimization of the conditions (pH, accumulation time, and accumulation potential), analytical curves were constructed for the analytes in the range from 1.0 × 10 to 2.0 × 10molL. The detection limits for HCT and TRT were 2.8 × 10 and 2.9 × 10molL, respectively. A high performance liquid chromatography method with diode array detection was also developed for the determination of HCT and TRT in hemodialysis samples, for comparison with the electroanalytical method.

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“…Nevertheless, these techniques have some disadvantages, such as high initial investment (equipment), the need for sample pre-treatments, time-consuming procedures, required expertise, and the high cost of consumables. In this sense, electroanalytical methods play a fundamental role and are stated as a very notable alternative for the determination of this anti-hypertensive drug [13][14][15][16][17][18]. In particular, voltammetric techniques provide excellent detection and quantification limits, high sensitivity and selectivity, with relatively low economic cost.…”

Section: Introductionmentioning

confidence: 99%

Voltammetric Determination of Anti-Hypertensive Drug Hydrochlorothiazide Using Screen-Printed Electrodes Modified with L-Glutamic Acid

et al. 2017

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This work deals with the development of screen-printed carbon electrodes modified with L-glutamic acid via two different approaches: electropolymerization (SPCE/PGA) and aryl diazonium electrochemical grafting (SPCE/EGA). SPCE/PGA and SPCE/EGA were analytically compared in the determination of hydrochlorothiazide (HCTZ) by differential pulse voltammetry. Both electrochemical characterization and analytical performance indicate that SPCE/EGA is a much better sensor for HCTZ. The detection and quantification limits were at the level of µmol L −1 with a very good linearity in the studied concentration range. In addition, the proposed SPCE/EGA was successfully applied for the determination of HCTZ in an anti-hypertensive drug with high reproducibility and good trueness.

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Electrochemical investigation of the voltammetric determination of hydrochlorothiazide using a nickel hydroxide modified nickel electrode

Cited by 30 publications

References 42 publications

Square Wave Voltammetry: An Alternative Technique to Determinate Piroxicam Release Profiles from Nanostructured Lipid Carriers

Square Wave Voltammetry: An Alternative Technique to Determinate Piroxicam Release Profiles from Nanostructured Lipid Carriers

Adsorptive stripping voltammetry for simultaneous determination of hydrochlorothiazide and triamterene in hemodialysis samples using a multi-walled carbon nanotube-modified glassy carbon electrode

Voltammetric Determination of Anti-Hypertensive Drug Hydrochlorothiazide Using Screen-Printed Electrodes Modified with L-Glutamic Acid

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