Electrochemical investigations of antioxidant interactions with radical anion and dianion of 1,3-dinitrobenzene

Revisiting the electrochemical formation, stability and structure of radical and biradical anionic structures in dinitrobenzenes

“…Also, for compounds I and II, an additional oxidation signal (Peak IIa ), appears upon inverting the potential at values more negative than the corresponding peak IIc. The behavior described here is consistent with the reported two successive one-electron transfer processes occurring in dinitrobenzenes [5,22,41] (Eqs. (1) and (2)).…”

“…For instance, the reduction of molecules bearing two nitro groups has gained attention in recent years [5][6][7][8] mainly due to the effects occurring in the stabilization of the corresponding electrogenerated radical anions by interacting groups present in the structure, since this phenomenon is known to be dependent on the environment surrounding the radical anion and on the method employed for its formation [6][7][8][9]. This issue is relevant, in biological and pharmacological terms, once the stability of the electrogenerated radical species is related to the capacity of these species to induce the formation of reactive oxygen species, in the presence of oxygen and after reduction [2][3][4][10][11][12] that in vivo or in cell occurs via the action of nitroreductases [2,11,12].…”

“…In terms of electrochemical behavior, the reduction of molecules bearing two reducible nitro groups in aprotic media [1,5] (A), is represented in the next set of chemical equations:…”

Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radical

“…By nature, antioxidants are weak acids and the OH group containing antioxidants are capable of donating proton(s). The increase in the reduction current of super oxide radical by the addition of hydroxyl group(s) containing flavonoids shows that electron is accepted or proton is donated by the flavonoid (Ziyatdinova et al 2005;Arshad et al 2009). To conclude which of the two processes occurred, the charge density values were analysed.…”

Cyclic Voltammetric Investigation of Interactions between Bisnitroaromatic Compounds and ds.DNA

“…The CV profiles matched with the reported correlation of the electrochemical responses of nitrocompounds containing the positional nitro-group(s) in their structures. 28,29 The electrochemical process for reduction peak at −1.097 V is attributable to nitro-group reduction product.…”