Electrochemical measurement of the antidiabetic potential of medicinal plants using multi-walled carbon nanotubes paste electrode

Mohiuddin, M.; Arbain, Dachyar; Islam, A.K.M. Shafiqul; Ahmad, Muhammad Syarhabil; Ahmad, Mardiana Idayu

doi:10.1134/s1023193514120027

Cited by 8 publications

(5 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9 ). Further increase in pH of the DNA hybridisation medium, the arowana DNA biosensor response increased abruptly at pH 7.0, after which a sharp decline in DPV current was discernible as the pH environment changed to basic condition due to the irreversible denaturation of DNA in the higher pH range [ 23 , 24 , 31 – 33 ]. Since maximum DPV response was acquired at a neutral pH, the next electrochemical evaluation of arowana DNA biosensor response was maintained at pH 7.0 using 0.05 M of Na-phosphate buffer.…”

Section: Resultsmentioning

confidence: 99%

A Highly Sensitive Electrochemical DNA Biosensor from Acrylic-Gold Nano-composite for the Determination of Arowana Fish Gender

Heng

Futra²,

Chiang

et al. 2017

Nanoscale Res Lett

View full text Add to dashboard Cite

The present research describes a simple method for the identification of the gender of arowana fish (Scleropages formosus). The DNA biosensor was able to detect specific DNA sequence at extremely low level down to atto M regimes. An electrochemical DNA biosensor based on acrylic microsphere-gold nanoparticle (AcMP-AuNP) hybrid composite was fabricated. Hydrophobic poly(n-butylacrylate-N-acryloxysuccinimide) microspheres were synthesised with a facile and well-established one-step photopolymerization procedure and physically adsorbed on the AuNPs at the surface of a carbon screen printed electrode (SPE). The DNA biosensor was constructed simply by grafting an aminated DNA probe on the succinimide functionalised AcMPs via a strong covalent attachment. DNA hybridisation response was determined by differential pulse voltammetry (DPV) technique using anthraquinone monosulphonic acid redox probe as an electroactive oligonucleotide label (Table 1). A low detection limit at 1.0 × 10−18 M with a wide linear calibration range of 1.0 × 10−18 to 1.0 × 10−8 M (R 2 = 0.99) can be achieved by the proposed DNA biosensor under optimal conditions. Electrochemical detection of arowana DNA can be completed within 1 hour. Due to its small size and light weight, the developed DNA biosensor holds high promise for the development of functional kit for fish culture usage.

show abstract

Section: Resultsmentioning

confidence: 99%

A Highly Sensitive Electrochemical DNA Biosensor from Acrylic-Gold Nano-composite for the Determination of Arowana Fish Gender

Heng

Futra²,

Chiang

et al. 2017

Nanoscale Res Lett

View full text Add to dashboard Cite

show abstract

“…Sharma, et al established that the Tharu community of Uttrakhand used the ground paste of leaves of E. laevis has been applied topically for the treatment of diverse skin disorders [18,21,33]. In another study, the antidiabetic perspective of E. laevis has been established through electrochemical measurement using multi-walled nano carbon tubes [76,231].…”

Section: Miscellaneous Activitiesmentioning

confidence: 99%

Phytochemical and Ethnopharmacological Perspectives of Ehretia laevis

et al. 2021

View full text Add to dashboard Cite

Ehretia laevis Roxb. (Boraginaceae) has been extensively used as a traditional remedy for the treatment of a diverse range of ailments related to the respiratory system, the gastrointestinal tract, the reproductive system, and against several infections. This review critically assesses and documents, for the first time, the fragmented information on E. laevis, including its botanical description, folklore uses, bioactive phyto metabolites and pharmacological activities. The goal is to explore this plant therapeutically. Ethnomedicinal surveys reveal that E. laevis has been used by tribal communities in Asian countries for the treatment of various disorders. Quantitative and qualitative phytochemical investigations of E. laevis showed the presence of important phytoconstituents such as pentacyclic triterpenoids, phenolic acids, flavonoids, fatty acids, steroids, alkaloids, aliphatic alcohols, hydrocarbons, amino acids, carbohydrates, vitamins and minerals. Fresh plant parts, crude extracts, fractions and isolated compounds have been reported to exhibit broad spectrum of therapeutic activities viz., antioxidant, antiarthritic, antidiabetic, anti-inflammatory, antiulcer, antidiarrheal, antidysenteric, wound healing and anti-infective activities. E. laevis is shown to be an excellent potential source of drugs for the mitigation of jaundice, asthma, dysentery, ulcers, diarrhea, ringworm, eczema, diabetes, fissure, syphilis, cuts and wounds, inflammation, liver problems, venereal and infectious disorders. Although few investigations authenticated its traditional uses but employed uncharacterized crude extracts of the plant, the major concerns raised are reproducibility of therapeutic efficacy and safety of plant material. The outcomes of limited pharmacological screening and reported bioactive compounds of E. laevis suggest that there is an urgent need for in-depth pharmacological investigations of the plant.

show abstract

“…Biological activity References Antioxidant activity Fruits [26] Anti-inflammatory activity Leaves [28] Antibacterial activity Leaves [28,30] Antiarthritic activity Leaves [21,27] Antidiabetic activity Leaves [31] All parts of the E. laevis plant are used for different medicinal purposes. Decoction of the fresh root and stem bark for diphtheria treatment is used for syphilis treatment.…”

Section: Plant Originmentioning

confidence: 99%

A general appraisal of Ehretia laevis Roxb: An essential medicinal plant

Sangode¹,

Tidke²,

Umekar³

2021

Int. J. Pharmacognosy Life Sci.

View full text Add to dashboard Cite

Ehretia laevis is a rare Indian medicinal plant used from ancient times. The plant is used for a variety of purposes, including ornaments, pot herbs, wood and stone dye, medicines, wines, and cosmetics. The inner bark of Ehretia laevis Roxb is used in the treatment of ulcers and headaches. Also useful in treatment for schizophrenia, absorption of calcium, muscle protein, post-surgery recovery, sports injuries, production of hormones, enzymes, antibodies. The plant has many uses that that many uses for different medicinal purposes. The fresh root is used in the treatment of syphilis, and the root is also used to treat diphtheria. Leaf powder mixed with sugar is divided into 10 equal doses. Each dose is taken daily along with goat milk curd to healing dysuria. The review focusing on the pharmacognostic parameters of E. Laevis and pharmacological uses.

show abstract

Electrochemical measurement of the antidiabetic potential of medicinal plants using multi-walled carbon nanotubes paste electrode

Cited by 8 publications

References 28 publications

A Highly Sensitive Electrochemical DNA Biosensor from Acrylic-Gold Nano-composite for the Determination of Arowana Fish Gender

A Highly Sensitive Electrochemical DNA Biosensor from Acrylic-Gold Nano-composite for the Determination of Arowana Fish Gender

Phytochemical and Ethnopharmacological Perspectives of Ehretia laevis

A general appraisal of Ehretia laevis Roxb: An essential medicinal plant

Contact Info

Product

Resources

About