Electrochemical monitoring of alcohol in sweat

Biscay, Julien; Findlay, Ewan; Dennany, Lynn

doi:10.1016/j.talanta.2020.121815

Cited by 26 publications

(15 citation statements)

References 91 publications

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“…It is known that from consumed and digested ethanol a measurable amount finds its way to and within the human skin, being secreted by the eccrine glands (primarily sweat glands) or during passive diffusion [14][15][16]. The potential effects of transdermal alcohol have been investigated in vitro and found that ethanol and its metabolite acetone increase the proliferation and mRNA expression of proliferation-associated genes (α5 integrin, cyclin D1 and keratinocyte growth factor receptor [KGFR]) in HaCaT keratinocytes and may thus increase the permeability of the skin, disrupting its barrier function [17].…”

Section: Alcohol and Keratinocytesmentioning

confidence: 99%

Alcohol in Psoriasis—From Bench to Bedside

Szentkereszty-Kovács

Gáspár

Szegedi

et al. 2021

IJMS

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Alcohol affects the symptoms, compliance and comorbidities as well as the safety and efficacy of treatments in psoriatic patients. In this review, we aim to summarize and link clinical observations with a molecular background, such as signaling pathways at the cellular level and genetic variations, and to provide an overview of how this knowledge could influence our treatment selection and patient management.

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Section: Alcohol and Keratinocytesmentioning

confidence: 99%

Alcohol in Psoriasis—From Bench to Bedside

Szentkereszty-Kovács

Gáspár

Szegedi

et al. 2021

IJMS

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“…41−46 For instance, Biscay et al reported an electrochemical sensor for ethanol monitoring in sweat. 47 The sensor utilized polyaniline-modified screen-printed carbon electrodes for the oxidation of ethanol in artificial sweat. Alferov et al developed methanol sensors by using a bio-selective membrane composed of four yeast alcohol oxides.…”

Section: ■ Introductionmentioning

confidence: 99%

“…One common type of sensor used for this purpose is electrochemical sensors. The basic component of these sensors include enzymes like alcohol dehydrogenase and alcohol oxidase. − For instance, Biscay et al reported an electrochemical sensor for ethanol monitoring in sweat . The sensor utilized polyaniline-modified screen-printed carbon electrodes for the oxidation of ethanol in artificial sweat.…”

Section: Introductionmentioning

confidence: 99%

Nanostructured Photonic Hydrogels for Real-Time Alcohol Detection

Ahmed

Elsherif

Park

et al. 2022

ACS Appl. Nano Mater.

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Rapid, reliable, and reusable sensors with a low limit of detection can play a vital role in alcohol detection, which is vital in a myriad of industries. Herein, hydrogel-based fiber optic probes were developed for alcohol sensing by a simple, rapid, and facile process. Aztec microstructures with a periodicity of 3 μm were imprinted onto alcohol-sensitive hydrogels for fabricating stand-alone and fiber optic sensors. The hydrogel matrix undergoes swelling in response to alcohol solutions, altering its diffraction efficiency. The real-time sensing capability of the developed sensors was demonstrated in response to various concentrations of ethanol, isopropanol, methanol, and dimethyl sulfoxide in the concentration range of 0 to 50 vol %. For the stand-alone sensors, sensitivities of 23, 21, and 15 μW/vol % were recorded for dimethyl sulfoxide (DMSO), isopropanol, and ethanol, respectively. For the optical fiber probes, sensitivities of 2.3, 2.2, 1.94, and 1.14 μW/vol % were recorded for DMSO, isopropanol, ethanol, and methanol, respectively. A fast response time of 20 s was recorded for both stand-alone and optical fiber sensors. Higher sensitivity toward DMSO was observed, with a low limit of detection of 0.5 vol %. The developed optical fiber sensors may have applications in remote and real-time alcohol sensing in forensics, medicine, food, and beverage manufacturing industries.

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“…Though alcohol is seen as a bond of emotion communication and a reliever of stress and anxiety, excessive alcohol consumption is harmful to personal health (e.g., high blood pressure, strokes, and liver troubles) and social order (e.g., violent behaviors and traffic accidents). , To date, there are many requirements for the development of ethanol detection devices, which works by urine, blood, saliva, breath, sweat, or verbal/interview measurements. , Several commercially available instruments are well developed as ex situ procedures. Breathalyzers, as the most commonly used device for measuring breath ethanol concentration, is susceptible to environmental state and personal factors .…”

Section: Introductionmentioning

confidence: 99%

Gold Nanowire Aerogel-Based Biosensor for Highly Sensitive Ethanol Detection in Simulated Sweat

Guan

Yang

et al. 2022

ACS Appl. Nano Mater.

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The devices with non-invasive characteristics have aroused people’s wide concern based on sweat analysis, such as providing real-time and accurate test of ethanol concentration. Unfortunately, these devices show limited selectivity, sensitivity, and stability owing to the existing planar electrodes with sluggish mass transport and inefficient active site utilization. The Au NW-gel bioelectrode exhibited good and quick linear current responses toward a broad range of ethanol concentration from 0.01 to 0.5 M. It was validated to an appreciable stability and selectivity to ethanol detection in the existences of sodium chloride, lactic acid, and urea. The abnormal concentration of ethanol in human’s biofluids is the index of unhealthy conditions from internal diseases. Herein, we introduce the application of gold nanowire aerogel (Au NW-gel) in detecting the concentration of ethanol in simulated human sweat. A preparation method based on substrate-assisted growth method is introduced. The length of Au NW synthesized by the substrate-assisted growth method is 10–20 μm. Au NW-gel has an ultralow density and high gold content, which can reduce the internal resistance of the electrode sufficiently. The pore structure of aerogel can accelerate the mass transfer process and make the Au NW-gel have excellent performance. The linear relationship between peak current and ethanol concentration in simulated sweat is established, and the retention capability of the biosensor is more than 83%. Furthermore, a simulation model is developed to validate the robust mass transfer and electrochemical performance of the porous electrode. The Au NW-gel-based electrode provides an effective pathway for detecting the ethanol content in sweat precisely.

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Electrochemical monitoring of alcohol in sweat

Cited by 26 publications

References 91 publications

Alcohol in Psoriasis—From Bench to Bedside

Alcohol in Psoriasis—From Bench to Bedside

Nanostructured Photonic Hydrogels for Real-Time Alcohol Detection

Gold Nanowire Aerogel-Based Biosensor for Highly Sensitive Ethanol Detection in Simulated Sweat

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