Electrochemical, optical and mass-based immunosensors: A comprehensive review of Bacillus anthracis detection methods

Tyśkiewicz, Renata; Fedorowicz, Magdalena; Nakonieczna, Aleksandra; Zielińska, Paulina; Kwiatek, Magdalena; Mizak, Lidia

doi:10.1016/j.ab.2023.115215

Cited by 5 publications

(2 citation statements)

References 75 publications

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“…A mass-based biosensor operates on the principle that binding events between the analyte and the biorecognition element cause a change in the overall mass of the biosensor system. − This mass change can be detected through a transducer, such as piezoelectric devices . By responding to mechanical stress, piezoelectric biosensors generate an electrical signal that can be correlated with the concentration of the analyte . An example of a mass-based biosensor is the quartz crystal microbalance (QCM) biosensor (Figure (b)). , This technology has found numerous applications in research and environmental monitoring .…”

Section: A Brief Introduction To Biosensorsmentioning

confidence: 99%

“… 82 By responding to mechanical stress, piezoelectric biosensors generate an electrical signal that can be correlated with the concentration of the analyte. 83 An example of a mass-based biosensor is the quartz crystal microbalance (QCM) biosensor ( Figure 3 (b)). 84 , 85 This technology has found numerous applications in research and environmental monitoring.…”

Section: A Brief Introduction To Biosensorsmentioning

confidence: 99%

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Biosensors for Public Health and Environmental Monitoring: The Case for Sustainable Biosensing

Williams,

Aguilar,

Pattiya Arachchillage

et al. 2024

ACS Sustainable Chem. Eng.

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Climate change is a profound crisis that affects every aspect of life, including public health. Changes in environmental conditions can promote the spread of pathogens and the development of new mutants and strains. Early detection is essential in managing and controlling this spread and improving overall health outcomes. This perspective article introduces basic biosensing concepts and various biosensors, including electrochemical, optical, mass-based, nano biosensors, and single-molecule biosensors, as important sustainability and public health preventive tools. The discussion also includes how the sustainability of a biosensor is crucial to minimizing environmental impacts and ensuring the long-term availability of vital technologies and resources for healthcare, environmental monitoring, and beyond. One promising avenue for pathogen screening could be the electrical detection of biomolecules at the single-molecule level, and some recent developments based on single-molecule bioelectronics using the Scanning Tunneling Microscopy-assisted break junctions (STM-BJ) technique are shown here. Using this technique, biomolecules can be detected with high sensitivity, eliminating the need for amplification and cell culture steps, thereby enhancing speed and efficiency. Furthermore, the STM-BJ technique demonstrates exceptional specificity, accurately detects single-base mismatches, and exhibits a detection limit essentially at the level of individual biomolecules. Finally, a case is made here for sustainable biosensors, how they can help, the paradigm shift needed to achieve them, and some potential applications.

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Section: A Brief Introduction To Biosensorsmentioning

confidence: 99%

Section: A Brief Introduction To Biosensorsmentioning

confidence: 99%

Biosensors for Public Health and Environmental Monitoring: The Case for Sustainable Biosensing

Williams,

Aguilar,

Pattiya Arachchillage

et al. 2024

ACS Sustainable Chem. Eng.

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Integration of microfluidic chips with biosensors

Sekhwama,

Mpofu,

Sudesh

et al. 2024

Discov Appl Sci

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The potential threat posed by disease outbreaks to diagnostic instruments demands the development of more effective biosensor technologies to counteract the risks. Diseases like SARS-CoV-2, Ebola, malaria, cholera, and many more have demonstrated beyond the limits of health care that new advancements are required for early detection and diagnosis. The rising number of diseases outbreaks has led to an increasing demand for biosensors that are more effective and quicker to utilize in healthcare settings. A biosensor incorporated with microfluidic chips offers an improved detection compared to traditional or classical biosensors. Microfluidic chips improve the performance of the biosensors by allowing automation, mixing, separation, throughput processing, and transport of the analytes to desired reactors. A biosensor incorporated with a microfluidic chip has improved sensitivity, easy operation and can use small volumes of samples to process the results. The effectiveness of biosensors depends also on the materials used in its fabrication and there are many materials used for fabrication which are reviewed in this work. This paper reviews the potential advantages of the use of microfluidic chips to enhance the performance of biosensors, materials used to fabricate the chips, and potential electrodes incorporated into microfluidic chips which improve the detection time by shortening the processing time for biosensors at the point of care service. This work also reviews new technologies which are not previously addressed other reviews including, integration of cell-imprinted polymers with microfluidic sensors and delved into future technologies outlook.

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Feasibility assessment of guided resonance modes in high Q and resolution mm-wave metamaterial biosensor

Ghafourivayghan,

Shabunin

2024

Optik

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Electrochemical, optical and mass-based immunosensors: A comprehensive review of Bacillus anthracis detection methods

Cited by 5 publications

References 75 publications

Biosensors for Public Health and Environmental Monitoring: The Case for Sustainable Biosensing

Biosensors for Public Health and Environmental Monitoring: The Case for Sustainable Biosensing

Integration of microfluidic chips with biosensors

Feasibility assessment of guided resonance modes in high Q and resolution mm-wave metamaterial biosensor

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