Electrochemical Oxidation of Metolazone at a Glassy Carbon Electrode

Pontinha, Ana Dora Rodrigues; Oliveira, Severino Carlos B.; Oliveira-Brett, Ana Maria

doi:10.1002/elan.200804352

Cited by 14 publications

(5 citation statements)

References 17 publications

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“…Due to its high speed and more sensitivity, SWV was used for the determination of detection limits and evaluation of thermodynamic parameters of DOPQ. Irreversibility of oxidation and reduction processes was confirmed at pH 7 by the same direction of forward and backward current components of both anodic and cathodic peaks 32 as shown in Figure 3.…”

Section: Resultssupporting

confidence: 54%

Redox Mechanism and Evaluation of Kinetic and Thermodynamic Parameters of 1,3‐Dioxolo[4,5‐g]pyrido[2,3‐b]quinoxaline Using Electrochemical Techniques

Shah

Rana

et al. 2014

Electroanalysis

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The electrochemical behavior of a biologically important heterocyclic compound, 1,3‐dioxolo[4,5‐g]pyrido[2,3‐b]quinoxaline was investigated by cyclic, square wave and differential pulse voltammetry in solutions of different pH. Kinetic and thermodynamic parameters like standard rate constant, diffusion coefficient, apparent energy of activation, standard Gibbs free energy and enthalpy and entropy changes were evaluated. Limits of detection and quantification were determined by square wave voltammetry. The redox mechanism of the compound was proposed on the basis of experimental results. Computational chemistry was used as a tool for the verification of experimental outcomes and assessment of different theoretical parameters

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Section: Resultssupporting

confidence: 54%

Redox Mechanism and Evaluation of Kinetic and Thermodynamic Parameters of 1,3‐Dioxolo[4,5‐g]pyrido[2,3‐b]quinoxaline Using Electrochemical Techniques

Shah

Rana

et al. 2014

Electroanalysis

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“…4. It is evident that the forward and backward components of the total current are in the same direction, 38 thus, indicating the irreversible nature of the oxidation processes of thiazoles.…”

Section: Square Wave and Differential Pulse Voltammetrymentioning

confidence: 94%

“…nF and E p = E • − 0.059 p n pH . 38 The same direction of forward and backward current components of total current of SWVs (Fig. 4) categorized the irreversible nature of the oxidation processes of ANT.…”

Section: Square Wave and Differential Pulse Voltammetrymentioning

confidence: 97%

“…The confirmation of reversible or irreversible nature of the redox process is an additional benefit of this technique due to its ability of recording forward and reverse current components of the net current in a single scan. 37,38 SWVs of 1 mM solutions of ANT and ATO in a medium of pH 7.4 can be seen in Fig. 4.…”

Section: Square Wave and Differential Pulse Voltammetrymentioning

confidence: 99%

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pH and Temperature Responsive Electrooxidation of Thiazole Derivatives and Preliminary Screening of Their Antioxidant Activity

Amjad

Lashin

Abbasi

et al. 2016

J. Electrochem. Soc.

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Thiazole and its derivatives have extensive pharmacological, industrial and biological applications. In the present work an attempt has been made to evaluate important physico-chemical parameters of two thiazole derivatives, 2-amino-5-nitrothiazole (ANT) and 2-amino-3-thioxothiazolidin-4-one (ATO) for proposing their redox mechanism using cyclic, square wave and differential pulse voltammetric techniques. Differential pulse voltammetry was conducted in media of different pH for the determination of acid base dissociation constant (pKa) and number of electrons and protons involved in proton coupled electron transfer processes. Cyclic voltammetry was employed for getting general voltammetric portrait of the compounds and evaluation of kinetic parameters like diffusion coefficient and heterogeneous electron transfer rate constant. Square wave voltammetry was performed for ensuring the reversible or irreversible nature of the redox reactions of the analytes. The feasibility of the redox reactions were estimated by computing the thermodynamic parameters by observing the effect of temperature on the anodic response of the compounds. Computational studies were carried out and the theoretical findings were found in line with the experimental results. Moreover, the compounds were screened for cytotoxicity and antioxidant activity.

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“…6B, indicating a mechanism involving the transfer of only one electron and no proton, occurring if the cdMC-LR oxidation product undergoes chemical deprotonation in more alkaline electrolytes. 31 The value of pK a z 9.2 for cdMC-LR was determined.…”

Section: Degraded Mc-lr Electrochemical Oxidation Behaviourmentioning

confidence: 99%

Microcystin-LR and chemically degraded microcystin-LR electrochemical oxidation

Lopes

Santos

Diculescu

et al. 2012

Analyst

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Sonoelectrochemical degradation (US-EC), a relatively new AOPs, is a technique that combined sonication (US) and electrolysis (EC) without the need for additional chemicals for the procedure. Microcystin-LR (MC-LR), as the most toxic and most widespread algal toxin, are threat to human health. Until now US-EC technique have never been applied to MC-LR decomposition. The aim of this paper is to study the effect of MC-LR degradation of US-EC, optimize the sonochemical and electrochemical parameters involved in MC-LR decomposition. US-EC degradation of MC-LR was better than US or EC alone in terms of time and degradation efficiency. The degradation rate of MC-LR was up to 93% applying US (20 kHz ,15 W) to the EC (6 mA cm-2) for 5min, and the residual concentration of MC-LR in the water was less than 1µg L-1 (the limits set by WHO). With processing time is extended to 10 minutes, the degradation rate was reached 99%.

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Electrochemical Oxidation of Metolazone at a Glassy Carbon Electrode

Cited by 14 publications

References 17 publications

Redox Mechanism and Evaluation of Kinetic and Thermodynamic Parameters of 1,3‐Dioxolo[4,5‐g]pyrido[2,3‐b]quinoxaline Using Electrochemical Techniques

Redox Mechanism and Evaluation of Kinetic and Thermodynamic Parameters of 1,3‐Dioxolo[4,5‐g]pyrido[2,3‐b]quinoxaline Using Electrochemical Techniques

pH and Temperature Responsive Electrooxidation of Thiazole Derivatives and Preliminary Screening of Their Antioxidant Activity

Microcystin-LR and chemically degraded microcystin-LR electrochemical oxidation

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