Electrochemical reduction of C-4 nitrosophenyl 1,4-dihydropyridines and their parent C-4 nitrophenyl derivatives in protic media

Cyclic voltammetry and scanning electrochemical microscopy studies of the heterogeneous electron transfer reaction of some nitrosoaromatic compounds

“…4A, it is also evident that the minimum value of k 0 app is at pH 8.5 where the electron transfer is the slowest, i.e., the system is more irreversible compared with the others pHs. This behavior agrees with that previously described [15] using differential pulse polarography. In that study, a break in the dependence of the peak potential with the pH of the medium was clearly observed at pH 9.…”

“…Recently a comprehensive study of the electrochemical reduction in protic media of C-4 nitrophenyl 1,4-DHPs and their corresponding nitrosophenyl 1,4-DHPs was published [15]. That electrochemical study concluded that the overall electroreduction mechanism of nitroso derivatives followed a two-electrons two-protons mechanism (Eq.…”

“…There is a report, however, on the electrochemical behavior of the photodegradation product of nifedipine, i.e., 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinecarboxylic acid dimethyl esther [7]. More recently [15], an electrochemical study was carried out of the reduction of a series of six C-4 nitrosophenyl 1,4-dihydropyridines and a comparison with the parent nitrophenyl derivatives. In that study, a 2-electron 2-proton mechanism was found for the electroreduction of the nitrosophenyl derivatives according to the following overall reaction:…”

Electrochemical preparation of conductive films of tetrapyridylporphyrins coordinated to four [Ru(5-NO2-phen)2Cl]+ groups

“…Nitro functional groups also present an important area for study since they are relevant in biolelectrochemistry and pharmacology [30], with well studied reduction mechanisms in both aqueous and organic solutions. Despite the rich redox chemistry of nitro functional groups, to the best of our knowledge no publications have been reported indicating its role as an electropolymerization precursor in coordination compounds containing transition metals.…”

The Electrochemical Reduction of Nitrophenols on Silver Globular Particles Electrodeposited under Pulsed Potential Conditions

“…These findings mean that the probable overall electrochemical reduction is based on the irreversible electrochemical process with a substantial diffusive character involving a complex multistep reduction with a 1:1 ratio of protons to electrons, as expected for the hydrogenation of nitrophenol species to give hydroxylamine and/or amine derivatives. 20,40,41 Table I summarizes some relevant results in terms of molar sensitivity ͑A mM −1 ͒, dependence of the peak potential on concentration and linear range obtained under voltammetric conditions. As can be seen, the molar sensitivity ͑A mM −1 ͒ decreases in the order: 2,4-DNP Ͼ 2,6,4-DCNP Ͼ 2,4-FNP Ͼ 2,4-CNP Ͼ 4-NP Ͼ 2,4-ANP and 4,2-MNP Ͼ 2-NP and 3-NP.…”