Electrochemical sensitive determination of acetaminophen in pharmaceutical formulations at iron oxide/graphene composite modified electrode

Palakollu, Venkata Narayana; Chiwunze, Tirivashe E.; Liu, Chen; Karpoormath, Rajshekhar

doi:10.1016/j.arabjc.2019.08.001

Cited by 38 publications

(20 citation statements)

References 36 publications

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“…Normally, is a safe analgesic agent, but excessive and long-term usage may lead to the accumulation of toxic metabolites, which leads to liver and kidney damage [ 226 ]. Electrochemical methods for PR determination are selective, rapid, low cost, and easy in handling in contrast with spectrometry, chromatography, or mass methods [ 227 ]. Different dyes were electrodeposited over carbon electrode surfaces as conductive polymeric films for the fabrication of PR electrochemical sensors.…”

Section: Electrochemical Sensors Based On Conducting Polymersmentioning

confidence: 99%

Electrochemical Sensors Based on Conducting Polymers for the Aqueous Detection of Biologically Relevant Molecules

et al. 2021

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Electrochemical sensors appear as low-cost, rapid, easy to use, and in situ devices for determination of diverse analytes in a liquid solution. In that context, conducting polymers are much-explored sensor building materials because of their semiconductivity, structural versatility, multiple synthetic pathways, and stability in environmental conditions. In this state-of-the-art review, synthetic processes, morphological characterization, and nanostructure formation are analyzed for relevant literature about electrochemical sensors based on conducting polymers for the determination of molecules that (i) have a fundamental role in the human body function regulation, and (ii) are considered as water emergent pollutants. Special focus is put on the different types of micro- and nanostructures generated for the polymer itself or the combination with different materials in a composite, and how the rough morphology of the conducting polymers based electrochemical sensors affect their limit of detection. Polypyrroles, polyanilines, and polythiophenes appear as the most recurrent conducting polymers for the construction of electrochemical sensors. These conducting polymers are usually built starting from bifunctional precursor monomers resulting in linear and branched polymer structures; however, opportunities for sensitivity enhancement in electrochemical sensors have been recently reported by using conjugated microporous polymers synthesized from multifunctional monomers.

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Section: Electrochemical Sensors Based On Conducting Polymersmentioning

confidence: 99%

Electrochemical Sensors Based on Conducting Polymers for the Aqueous Detection of Biologically Relevant Molecules

et al. 2021

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“…Due to synergistic effects on the electrochemical performance of devices, nanocomposites can be useful to improve the resolution and the selectivity, especially when multi-analyte detection of close species is desirable. Table 4 [ [19] , [25] , [75] , [76] , [77] , [78] , [79] , [80] , [81] , [82] , [83] , [84] , [85] , [86] , [87] , [88] , [89] , [90] , [91] , [92] , [93] , [94] , [95] , [96] , [97] , [98] , [99] , [100] , [101] , [102] , [103] , [104] , [105] , [106] , [107] , [108] , [109] , [110] , [111] , [112] , [113] , [114] , [115] , [116] , [117] , [118] , [119] , [120] , [121] , [122] , [123] ] shows the analytical response characteristics of PCT sensors based on nanocomposite modified electrodes.…”

Section: Nanocomposites Modifiersmentioning

confidence: 99%

“…Exhaustive interference experiments revealed that the sensor possessed high level of selectivity. PCT was also determined on RGO + Fe 2 O 3 [ 78 ] and RGO + NCeO 2 [ 79 ] modified electrodes by DPV with LOD of 0.0098 and 0.021 μM, respectively. These modified electrodes were successfully used for PCT determination in real samples with good selectivity and sensitivity to interfering influence.…”

Section: Nanocomposites Modifiersmentioning

confidence: 99%

“…Chemical modification of carbon-based electrode had apparently resulted in an elimination of the interferences effects in pharmaceutical and biological samples. Many of the sensors developed were successfully applied to the determination of PCT in biological samples, such as human urine [ 17 , 34 , 44 , 57 , 69 , 78 , [82] , [83] , [84] , [85] , [86] , [87] , 90 , 91 , 96 , 99 , 104 , 106 , 108 , 110 , 113 , 116 , 123 ] and serum [ 18 , 35 , 39 , 43 , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [63] , [64] , [65] , 97 , 99 , 100 , 103 , [112] , [113] , [114] , [115] , [116] , [117] , 120 , 123 ], enabling the use of PCT as a relevant biomarker of several diseases. Another common application of the fabricated sensors was the determination of the PCT in pharmaceutical samples [ 34 , 36 , 38 , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , ...…”

Section: Critical Issues In Pct Detectionmentioning

confidence: 99%

“…The selection of the most suitable electrochemical technique is an important factor for the achievement of high selectivity and detecting trace levels of PCT. CV [ 25 , 58 , 67 , 72 ], DPV [ 18 , 19 , 40 , 43 , [52] , [53] , [54] , [55] , [56] , [57] , [59] , [60] , [61] , [62] , [64] , [65] , [66] , [67] , [68] , 70 , 72 , 73 , [76] , [77] , [78] , [79] , [83] , [84] , [85] , 87 , 89 , 92 , 93 , 95 , 97 , 98 , 101 , 103 , 106 , 108 , [110] , [111] , [112] , [113] , [114] , [115] , 119 , [121] , [122] , [123] , [125] , [126] , [127] , [128] , [129] , [130] , [131] , [132] , 134 ] and SWV [ 17 , 34 , 36 , 38 , 41 , 75 ...…”

Section: Critical Issues In Pct Detectionmentioning

confidence: 99%

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Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples

Boumya

Taoufik

Achak

et al. 2021

Journal of Pharmaceutical Analysis

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Paracetamol is a non-steroidal, anti-inflammatory drug widely used in pharmaceutical applications for its sturdy, antipyretic and analgesic action. However, an overdose of paracetamol can cause fulminant hepatic necrosis and other toxic effects. Thus, the development of advantageous analytical tools to detect and determine paracetamol is required. Due to simplicity, higher sensitivity and selectivity as well as costefficiency, electrochemical sensors were fully investigated in last decades. This review describes the advancements made in the development of electrochemical sensors for the paracetamol detection and quantification in pharmaceutical and biological samples. The progress made in electrochemical sensors for the selective detection of paracetamol in the last 10 years was examined, with a special focus on highly innovative features introduced by nanotechnology. As the literature is rather extensive, we tried to simplify this work by summarizing and grouping electrochemical sensors according to the by which manner their substrates were chemically modified and the analytical performances obtained.

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Detection and Treatment of Persistent Pollutants in Water: General Review of Pharmaceutical Products

2022

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Environmental problems of great complexity arise from the enormous number of toxic substances that are generated by anthropogenic activities. Seemingly, society encounters new issues every day thus these problems seem to be endless. Now in the face of the COVID‐19 pandemic and the SARS‐CoV‐2 crisis, a large number of emerging treatment compounds generated by pharmaceutical companies worldwide makes future issues even more treacherous. For this reason, there is an increasing need to detect and treat emerging compounds to prevent them from becoming persistent pollutants. This review describes the advances in the use of electrochemical sensors with modified carbon‐based electrodes among other issues, to determine antibiotics, anti‐inflammatories and antidepressants levels in the environment. It further explores technologies suggested for cleaning wastewater polluted by pharmaceutical products using biological or advanced oxidation processes including photolysis, photocatalysis, microwave heating, ultrasound, Fenton, electro‐Fenton, photoelectro‐Fenton and various combined treatments.

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Electrochemical sensitive determination of acetaminophen in pharmaceutical formulations at iron oxide/graphene composite modified electrode

Cited by 38 publications

References 36 publications

Electrochemical Sensors Based on Conducting Polymers for the Aqueous Detection of Biologically Relevant Molecules

Electrochemical Sensors Based on Conducting Polymers for the Aqueous Detection of Biologically Relevant Molecules

Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples

Detection and Treatment of Persistent Pollutants in Water: General Review of Pharmaceutical Products

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