ical [2].Forming Pt-based alloys with transi tion metal is a potent strategy to remarkably reduce the usage of noble metal, and therefore enhance the catalytic activity [8−19]. For alloy catalysts, the differe nt arrangements of dissimilar atoms on the surface or subsurface could modify the electronic structure [20,21] , commonly show extraordinary electrocatalytic performance. Coupling such shape-controlled synthesis with post-t reatments is an effective strategy to prepare effective and highly active catalysts. As a general post-treatment, acid leaching is the main method [29−32] to form active and rough skeleton surface. Compared with other post-treatments, acid leaching has the following advantages: (a) acid can remove some specific surfactants used in soft-template synthesis; (b) acid leaching does not decrease the dispersing ability; (c) acid leaching is milder, simpler and more practical [32,33].Furthermore, compared with zero-dimensional (0D) materials, one-dimensional (1D) materials are thought to alleviate all natural drawbacks of 0D materials for enhancing stability. The Ostwald ripening [34], support break-A BSTRACT Forming alloys with transition metal remarkably decreases the u sage of noble metal and offers benefits for electrocatalysis. Here we introduced a mixed-solvent strategy to synthesize unique PtAuCu ternary nanotubes (NTs) with porous and rough surface, using high quality Cu nanowires (NWs) as the partial sacrificial templates. We found that Au plays a key role in the enhancement of e lectrocatalytic performance for both methanol oxidation reaction (MOR) and formic acid oxidation reaction (FAOR). The mass activities of PtAuCu NTs after acid leaching for MOR and FAOR reach 1698.8 mA mg