Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture

Hu, Huimin; Wang, Xiaodong; Huang, Yan-Sheng; He, Bao-Rong; Jia, Bin; Sun, Kai; Hao, Dingjun; Guo, Yunshan

doi:10.1016/j.jmrt.2022.03.040

Cited by 8 publications

(4 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Even though similar results were shown by the samples immersed in SBF [50,52,53], a slightly different behaviour was promoted by the electrolyte change. Higher semicircle diameters were obtained when DMEM was used, also confirmed by higher impedance modulus revealed by the Bode amplitude plot (Figure 7b).…”

Section: In Vitro Eis Resultssupporting

confidence: 77%

“…In this case, in addition to the often-used two-time constant equivalent circuit (with a CPE instead of ideal dielectric properties caused by inhomogeneity or current leakage [56]), L was also added, ascribed to corrosion product formation. Even though similar results were shown by the samples immersed in SBF [50,52,53], a slightly different behaviour was promoted by the electrolyte change. Higher semicircle diameters were obtained when DMEM was used, also confirmed by higher impedance modulus revealed by the Bode amplitude plot (Figure 7b).…”

Section: In Vitro Eis Resultssupporting

confidence: 77%

See 1 more Smart Citation

Effect of Deposition Temperature on the Structure, Mechanical, Electrochemical Evaluation, Degradation Rate and Peptides Adhesion of Mg and Si-Doped Hydroxyapatite Deposited on AZ31B Alloy

et al. 2023

View full text Add to dashboard Cite

Degradable and non-degradable biomaterials are two categories that can be used to classify the existing biomaterials, being a solution for eliminating a second surgical intervention of the implant when the tissue has properly recovered. In the present paper, the effect of deposition temperature on the structure, morphology, hardness, electrochemical evaluation, degradation properties and functional peptides adhesion of Mg and Si-doped hydroxyapatite was investigated. The coatings were obtained by RF magnetron sputtering technique at room temperature (RT) and 200 °C on AZ31B alloy substrate. Results showed that an increase in deposition temperature led to an improvement in hardness and reduced modulus of about 47%. From an electrochemical point of view, a comparative assessment of corrosion resistance was made as a function of the immersion medium used, highlighting the superior behaviour revealed by the coating deposited at elevated temperature when immersed in DMEM medium (icorr~12 µA/cm2, Rcoat = 705 Ω cm2, Rct = 7624 Ω cm2). By increasing the deposition temperature up to 200 °C, the degradation rate of the coatings was slowed, more visible in the case of DMEM, which had a less aggressive effect after 14 days of immersion. Both deposition temperatures are equally suitable for further bio-inspired coating with a mussel-derived peptide, to facilitate biointegration.

show abstract

Section: In Vitro Eis Resultssupporting

confidence: 77%

Section: In Vitro Eis Resultssupporting

confidence: 77%

Effect of Deposition Temperature on the Structure, Mechanical, Electrochemical Evaluation, Degradation Rate and Peptides Adhesion of Mg and Si-Doped Hydroxyapatite Deposited on AZ31B Alloy

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Material properties, mechanical properties, and biocompatibility are the main factors affecting the safety and effectiveness of surgery. [1][2][3][4][5] Although the commonly used bone plate materials (such as titanium alloy, stainless steel, cobalt-based alloy, etc.) have strong advantages in strength, toughness, and elastic modulus, they differ significantly in mechanical properties from those of human bones.…”

Section: Introductionmentioning

confidence: 99%

Study of in vitro wear resistance and degradation properties of self-made treated medical magnesium alloys

Yuan,

Guo,

Gao

et al. 2024

AIP Advances

View full text Add to dashboard Cite

Magnesium alloy shows promise of becoming a new generation of degradable biomaterials because of its good biocompatibility and mechanical properties. This paper details the preparation of magnesium alloy by adding calcium and zinc elements to pure magnesium at a specific ratio and strengthened by solid solution treatment and extrusion. The magnesium alloy is subjected to micro-motion wear testing, in vitro degradation product analysis, and in vitro biocompatibility testing and demonstrates excellent performance. The study demonstrates that the prepared Mg-2.0Zn-1.6Ca alloy friction ring has an elliptical shape with a low friction coefficient, which notably enhances the wear resistance of the material. Furthermore, the corrosion of magnesium alloy products in simulated body fluids does not adversely affect the human body. This is because the surface of the magnesium alloy favors cell growth and has excellent antimicrobial properties. The purpose of this paper is to enhance the preparation, surface friction properties, and biocompatibility of magnesium alloys and to provide theoretical and practical guidance for the preparation, processing, and application of high-performance medical magnesium alloys.

show abstract

“…Some of the Mg alloys such as Mg-Zn-Ca [ 28 ], Mg-Ca-La [ 29 ], Mg-Sr [ 30 ], Mg-Mn-Ca-Zn [ 31 ] demonstrated bio-safe degradation rates in the range of 0.2–0.5 mm/year in physiological media due to their tendency to form noble composite oxide layers which act as effective shields against aggressive ions of physiological media [ 32 ]. Nowadays, various ceramic reinforcements including β-TCP [ 33 ], HA [ 34 ], and calcium polyphosphate (CPP) [ 35 ] have also been reported to enhance corrosion resistance, bioactivity and mechanical strength of Mg alloys. However, the versatility of their bio-functionalities for clinical qualification is yet to be established.…”

Section: Introductionmentioning

confidence: 99%

Progress in bioactive surface coatings on biodegradable Mg alloys: A critical review towards clinical translation

Singh

Batra

Kumar

et al. 2023

Bioactive Materials

View full text Add to dashboard Cite

Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture

Cited by 8 publications

References 46 publications

Effect of Deposition Temperature on the Structure, Mechanical, Electrochemical Evaluation, Degradation Rate and Peptides Adhesion of Mg and Si-Doped Hydroxyapatite Deposited on AZ31B Alloy

Effect of Deposition Temperature on the Structure, Mechanical, Electrochemical Evaluation, Degradation Rate and Peptides Adhesion of Mg and Si-Doped Hydroxyapatite Deposited on AZ31B Alloy

Study of in vitro wear resistance and degradation properties of self-made treated medical magnesium alloys

Progress in bioactive surface coatings on biodegradable Mg alloys: A critical review towards clinical translation

Contact Info

Product

Resources

About