Electrochemical Tuning by Polarized UV Light Induced Molecular Orientation of Chiral Salen-type Mn(II) and Co(II) Complexes in an Albumin Matrix

Abstract

Abstract:The authors have prepared supramolecular systems as artificial metalloproteins composed of several chiral salen-type Mn(II) and Co(II) complexes in a HSA (human serum albumin) matrix. The docking was discussed by UV-vis spectral changes and a ligand-protein docking simulation program. After linearly polarized UV light irradiation, that anisotropy of molecular orientation of the complexes increased was confirmed by polarized IR spectra. The authors have observed that the electrochemical behavior of the aligned complexes incorporating diphenyl groups in HSA can be tuned without UV radiation damage of HSA higher structures.

Introductory Chapter: Chirality from Molecular Electronic States

“…In the case of chiral salen-type metal complexes, it is not easy to investigate their electronic properties using both experimental and theoretical methods. Previously, we have systematically studied on preparations, crystal structures, and electronic states for mononuclear (3d) [25][26][27] and binuclear (3d-4f) [28][29][30][31][32] complexes. Besides X-ray crystallography and IR spectra, CD and UV-vis spectra, XAS spectra, fluorescence spectra, and magnetic measurements were used.…”

“…Even employing achiral metal complexes, such hybrid assembly must be a chiral material, which can be experimentally elucidated by means of chiroptical spectroscopy (CD or VCD) [25] as well as quenching of fluorescence intensity (obeying Stern-Volmer plot) [26]. However, calculations of electronic state for such hybrid assembly must be difficult only by means of these conventional or commercially available programs at present [27].…”

Linearly Polarized UV Light-Induced Optical Anisotropy of PVA Films and Flexible Macrocycle Schiff Base Ni(II), Cu(II), Zn(II) Dinuclear Complexes

“…However, the power to control their alignment may be weaker than in azo-compounds, due to the Weigert effect. Previously, we have attempted to compare some dinuclear complexes with/without azo-compounds [22,23]. Such a strategy may be promising to employ various metal complexes more freely than the separated composites of the azo-compounds and metal complexes, when using electronic properties derived from the organic ligand moieties.…”