Electrochemically-assisted deposition of biomimetic hydroxyapatite–collagen coatings on titanium plate

Manara, Silvia; Paolucci, Francesco; Palazzo, Barbara; Marcaccio, Massimo; Foresti, Elisabetta; Tosi, Giorgio; Sabbatini, Simona; Sabatino, Piera; Altankov, George; Roveri, Norberto

doi:10.1016/j.ica.2007.03.044

Cited by 80 publications

(47 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…169 In preparing the electrolyte, proper amounts of − ↔ H 2 During the electrochemical process, the pH increases up to about 9.0-10.0 around the cathode, leading the precipitation of a mineral apatitic phase on the cathode electrode. [170][171][172] It is possible to obtain also calcium-phosphate/collagen coating on titanium surface with cell containing slightly acidic collagen molecules (soluble type I collagen was added to the electrolyte at the concentration of 0.012%, w/v) and Ca 2+ and PO 4 3− ions aqueous solution. In such a process, the collagen/calcium phosphate composite formation involves the self-assembly of collagen molecules into reconstituted fibrils during the contemporary crystallization of calcium phosphate mineral on the electrode surface.…”

Section: Biomimetic Nanohydroxyapatite Coatingmentioning

confidence: 99%

“…169 In an electrochemical cell composed of two electrodes, the nucleation-crystallization of carbonate-hydroxyapatite and the collagen molecules self-assembling of collagen fibers take place simultaneously for effect of the pH raising on the titanium electrode surface, allowing the formation of a nanostructured hydroxyapatite/ collagen biomimetic coating. 170 In order to well visualize the collagen fibrils electrochemically deposited on the cathode, the collagen fibrilshydroxyapatite nanocrystals hybrid coating can be decalcified in a 10 wt% EDTA solution for 24 h before being examined by SEM (Figure 9). …”

Section: Biomimetic Nanohydroxyapatite Coatingmentioning

confidence: 99%

See 1 more Smart Citation

Evolving application of biomimetic nanostructured hydroxyapatite

Roveri¹,

Iafisco²

2010

NSA

View full text Add to dashboard Cite

By mimicking Nature, we can design and synthesize inorganic smart materials that are reactive to biological tissues. These smart materials can be utilized to design innovative thirdgeneration biomaterials, which are able to not only optimize their interaction with biological tissues and environment, but also mimic biogenic materials in their functionalities. The biomedical applications involve increasing the biomimetic levels from chemical composition, structural organization, morphology, mechanical behavior, nanostructure, and bulk and surface chemical-physical properties until the surface becomes bioreactive and stimulates cellular materials. The chemical-physical characteristics of biogenic hydroxyapatites from bone and tooth have been described, in order to point out the elective sides, which are important to reproduce the design of a new biomimetic synthetic hydroxyapatite. This review outlines the evolving applications of biomimetic synthetic calcium phosphates, details the main characteristics of bone and tooth, where the calcium phosphates are present, and discusses the chemical-physical characteristics of biomimetic calcium phosphates, methods of synthesizing them, and some of their biomedical applications.

show abstract

Section: Biomimetic Nanohydroxyapatite Coatingmentioning

confidence: 99%

Section: Biomimetic Nanohydroxyapatite Coatingmentioning

confidence: 99%

Evolving application of biomimetic nanostructured hydroxyapatite

Roveri¹,

Iafisco²

2010

NSA

View full text Add to dashboard Cite

show abstract

“…The advanced analog and digital circuit designs and innovative software and hardware provide superior multitasking control for scanning probe microscopes (SPMs). 42,43 The samples in contact mode using a J scanner and silicon nitride tips (200 lm long with nominal spring constant 0.06 N/m).…”

Section: Morphological Characterizationmentioning

confidence: 99%

Different corrosive effects on hydroxyapatite nanocrystals and amine fluoride-based mouthwashes on dental titanium brackets: a comparative in vitro study

Lelli¹,

Marchisio²,

Foltran³

et al. 2013

IJN

View full text Add to dashboard Cite

Titanium plates treated in vitro with a mouthwash containing amine fluoride (100 ppm F − ) and another containing zinc-substituted carbonate-hydroxyapatite have been analyzed by scanning electron microscopy and atomic force microscopy to evaluate the modification of the surface roughness induced by treatment with these two different mouthwashes.The treatment with F − -based mouthwash produces a roughness characterized by higher peaks and deeper valleys in the streaks on the titanium bracket surface compared with those observed in the reference polished titanium plates. This effect causes a mechanical weakness in the metallic dental implant causing bacterial growth and therefore promotes infection and prosthesis contamination. However, the in vitro treatment with a mouthwash containing zincsubstituted carbonate-hydroxyapatite reduced the surface roughness by filling the streaks with an apatitic phase. This treatment counteracts the surface oxidative process that can affect the mechanical behavior of the titanium dental implant, which inhibits the bacterial growth contaminating prostheses.

show abstract

“…Several attempts have been made to improve the bonding between bone and a dental implant by coating the titanium of the implant with bioactive materials, like hydroxyapatite, which can form a chemical bond with bone tissue [1][2][3][4] . Despite the development of this coating method, implants have continued to fail.…”

Section: Introductionmentioning

confidence: 99%

The biomimetic apatite-cefalotin coatings on modified titanium

et al. 2012

View full text Add to dashboard Cite

Dental implant failure often occurs due to oral bacterial infection. The aim of this study was to demonstrate that antibiotic efficacy could be enhanced with modified titanium. First, the titanium was modified by anodization and heat-treatment. Then, a biomimetic coating process was completed in two steps. Surface characterization was performed with scanning electron microscopy, energy dispersive spectroscopy, and X-ray diffraction. Release of antibiotic was evaluated by UV/VIS spectrometry, and the antibacterial effect was evaluated on Streptococcus mutans. After the second coating step, we observed a thick homogeneous apatite layer that contained the antibiotic, cefalotin. The titanium formed a rutile phase after the heat treatment, and a carbonated apatite phase appeared after biomimetic coating. We found that the modified titanium increased the loading of cefalotin onto the hydroxyapatite coated surface. The results suggested that modified titanium coated with a cefalotin using biomimetic coating method might be useful for preventing local post-surgical implant infections.

show abstract

Electrochemically-assisted deposition of biomimetic hydroxyapatite–collagen coatings on titanium plate

Cited by 80 publications

References 40 publications

Evolving application of biomimetic nanostructured hydroxyapatite

Evolving application of biomimetic nanostructured hydroxyapatite

Different corrosive effects on hydroxyapatite nanocrystals and amine fluoride-based mouthwashes on dental titanium brackets: a comparative in vitro study

The biomimetic apatite-cefalotin coatings on modified titanium

Contact Info

Product

Resources

About