“…The suppressor is one of the key components in IC and can reduce the background conductance of the eluent and simultaneously enhance the analyte signal. Various types of suppressors have been developed in the past decades to achieve higher sensitivity, including packed column [1], hollow fiber [2] or monofilament filled fiber [3], micro membrane-based suppressor operated in chemical [4] or electrolytic mode [5,6]. Most of the above devices were designed for conventional IC systems, and less work has been done on capillary IC (CIC), despite the facts that CIC has several advantages over conventional IC such as higher separation efficiency, lower eluent consumption, and easier coupling with MS.…”