Electrochemically Induced, Metal Free Synthesis of 2‐substituted chroman‐4‐ones
Mohsen Monirialamdari,
Aleksandra Podlaska,
Dominika Pomikło
et al.
Abstract:Electrochemically induced, decarboxylative functionalization of chromone‐3‐carboxylic acids by N‐hydroxyphthalimide esters as alkyl radical precursors was studied. Electrochemical protocol offers a sustainable and green approach, obviating the need for catalysts, relying on the direct reduction of NHPI esters using electric current. Developed protocol provides a straightforward route to the synthesis of diverse molecules with potential biological activity.
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