Electrochemically promoted annulation of aldehydes and carbazates: access to 2-alkoxy/aryloxy-5-substituted 1,3,4-oxadiazole and 1,3,4-oxadiazol-2(3H)-one derivatives

Abstract

An efficient and eco-friendly synthesis of chemically and pharmaceutically interesting 2-alkoxy/aryloxy-1,3,4-oxadiazoles, and 1,3,4-oxadiazol-2(3H)-ones has been developed through the annulation of aldehydes and carbazates. The protocol involves electrochemical-promoted access of the...