Electrochemiluminscence Based Biosensors with AuNP Showing Catalytic ROS Generation

Abstract

Electrochemiluminescence (ECL) has been a useful analytical tool for fields such as molecular biology, food analysis, and analytical chemistry. In situ generation of reactive oxygen species (ROS) by surface mediated catalysis works collaboratively with the luminol based ECL system. This work describes an ECL strategy involving in situ ROS generation from the surface of gold nanoparticles (AuNP). We reported on a novel condition to induce AuNP catalysis, and examined the application of this phenomenon to an immunosensing platform based on AuNP catalysis and ECL.