Electroconvulsive therapy for schizophrenia

Tharyan, Prathap; Ce, Adams

doi:10.1002/14651858.cd000076

Cited by 50 publications

(104 citation statements)

References 117 publications

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“…Depressed women treated with ECT have a full or partial response to treatment in 84% of cases, and for schizophrenic women this rate is 61%. These results are similar to response rates in non-pregnant samples of depressed and schizophrenic women [61][62][63]. In addition, ECT acts more quickly than pharmacotherapy such as antidepressants [64].…”

Section: Discussionsupporting

confidence: 72%

Electroconvulsive treatment during pregnancy: a systematic review

Pompili

Dominici

Giordano

et al. 2014

Expert Review of Neurotherapeutics

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Pharmacological treatment of severe psychiatric disorders during pregnancy is complicated by the potential harmful effects of treatment for the fetus. Electroconvulsive therapy (ECT) has been demonstrated to be effective for the treatment of several mental disorders. The aim of this study was to investigate the safety of ECT in the treatment of psychiatric disorders during pregnancy; to compare its efficacy with medication; and to identify the main indications for use in pregnancy. We performed a careful and systematic review of the literature on ECT and pregnancy was conducted. Almost all patients demonstrated total or at least partial remission of symptoms after ECT treatment. No deaths were reported in ECT-treated pregnant women. We conclude that ECT is probably currently under-used in many psychiatric settings because of its stigmatized perception by patients and by mental health professionals. ECT seems to be effective for treating major psychiatric disorders during pregnancy, and the risks of adverse events are low.

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Section: Discussionsupporting

confidence: 72%

Electroconvulsive treatment during pregnancy: a systematic review

Pompili

Dominici

Giordano

et al. 2014

Expert Review of Neurotherapeutics

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“…17 Similarly, a recent survey from 45 Asian countries showed that schizophrenia was the commonest indication for ECT. 21 A Cochrane review 22 revealed that there is a role for use of ECT combined with antipsychotics in schizophrenia when rapid response is needed or in treatment-resistant patients. However, ECT guidelines in the western hemisphere rarely support the use of ECT in schizophrenia 23,24 It is unclear if ECT should be indicated in schizophrenia from the research evidence available at present.…”

Section: Comparison Of Results To Available Literaturementioning

confidence: 99%

Comparison of Electroconvulsive Therapy Practice Between London and Bengaluru

Eranti

Thirthalli²,

Pattan³

et al. 2011

The Journal of ECT

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The practice of ECT differed substantially between the London and Bengaluru sites. The relatively limited use of ECT in London reflects local treatment guidelines and may reflect the stigma associated with ECT. Electroconvulsive therapy is more widely used in Bengaluru with good outcomes. Further cross-cultural research is required to study the reasons for such contrasting practices and what constitutes the optimal practice of ECT for health systems in different countries.

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“…Unfortunately, there are no studies that compare ECT with (either conventional or atypical) antipsychotic drugs in TRS patients; only case reports and case series are present in literature [31,[33][34][35][36][37].…”

Section: Previous Studies On the Efficacy Of Ectmentioning

confidence: 99%

“…However, others have noted that there has been no evidence to clearly refute the use of ECT for patients with schizophrenia. There is some limited evidence to support its use, particularly combined with antipsychotic drugs, in schizophrenic patients who show limited response to medication alone [31]. Recently, the UK's National Institute for Clinical Excellence (NICE) published their opposite opinion [32] that the current state of evidence did not allow the general use of ECT in the management of schizophrenia (Table 3).…”

Section: Introductionmentioning

confidence: 99%

Electroconvulsive Therapy for Schizophrenia

Chanpattana¹

2007

CPSR

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The role of electroconvulsive therapy (ECT) in treating patients with schizophrenia remains unclear. This paper aims to determine whether ECT results in clinically meaningful benefit with regard to psychopathology, behavior and functioning for patients with schizophrenia, and whether variations in the practical administration of ECT influences outcome. Existing research in the field and the new information of research in patients with treatment-resistant schizophrenia (TRS) from Thailand are summarized. Independent of gender, duration of the current episode and severity of baseline negative symptoms predict outcome. Treatment results in marked improvement in positive symptoms, with an intermediate effect on affective symptoms, and no effect or worsening of negative symptoms. The combination of ECT and conventional antipsychotic drug is associated with better outcome than either ECT alone or antipsychotic drug alone during both acute and maintenance phases of treatment. This improvement is not only in psychopathology but also in quality of life and social functioning. Electrical stimulus doses 2-4 times the seizure threshold are likely to increase the speed of recovery with bilateral ECT. Thrice-weekly ECT elicits response faster than does twice-weekly ECT. Although this preliminary evidence supports the use of ECT in patients with TRS, the research base for its use is still inadequate and deserves better investigation.

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Electroconvulsive therapy for schizophrenia

Cited by 50 publications

References 117 publications

Electroconvulsive treatment during pregnancy: a systematic review

Electroconvulsive treatment during pregnancy: a systematic review

Comparison of Electroconvulsive Therapy Practice Between London and Bengaluru

Electroconvulsive Therapy for Schizophrenia

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