Electrodeposition of chitosan/gelatin/nanosilver: A new method for constructing biopolymer/nanoparticle composite films with conductivity and antibacterial activity

Wang, Yifeng; Guo, Xuecheng; Pan, Ruihao; Han, Di; Chen, Tao; Geng, Zenghua; Xiong, Yan; Chen, Yanjun

doi:10.1016/j.msec.2015.04.031

Cited by 68 publications

(36 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The agar surface was inoculated by dipping sterile cotton swabs into a cell suspension and by streaking the plate surface in three directions. The plate was allowed to dry for 20 min, and the films were then placed onto the surface of agar, and incubated in air at 28°C for 24 h. The halo zone of complete inhibition was determined using a caliper and the mean value for each organism was recorded (Wang et al, 2015).…”

Section: Swelling Indexmentioning

confidence: 99%

Effect of drug incorporation technique and polymer combination on the performance of biopolymeric antifungal buccal films

Tejada

Lamas

Svetaz

et al. 2018

International Journal of Pharmaceutics

View full text Add to dashboard Cite

Numerous films with a dissolved or dispersed active principle within a polymeric matrix have been described in literature. However, the incorporation of solid crystals into the films may influence several relevant properties. Additionally, it has been reported that different polymeric matrices lead to films presenting a different performance. The aim of this work was to evaluate the effect of the combination of chitosan with carrageenan (κ-, λ-, and ι-) as matrices, and of the miconazole nitrate incorporation method, on the films behavior. Mechanical properties, drug release and antifungal activity were evaluated. The state of the drug in the films was analyzed by different techniques. Films showed a homogeneous surface and a thermal protective effect on the drug. The combination of chitosan and λ-carrageenan leads to films with the highest values of tensile and mucoadhesive strength. Films with solubilized drug displayed slightly higher elongation at break, tensile and mucoadhesive strength and faster drug release than those with suspended miconazole nitrate. However, no differences were found regarding the antifungal activity of the different formulations including time-to-kill curves.

show abstract

Section: Swelling Indexmentioning

confidence: 99%

Effect of drug incorporation technique and polymer combination on the performance of biopolymeric antifungal buccal films

Tejada

Lamas

Svetaz

et al. 2018

International Journal of Pharmaceutics

View full text Add to dashboard Cite

show abstract

“…Figure shows UV‐visible spectrum of the n‐CHS, h,n‐CHS, m,n‐CHS, and h,m,n‐CHS. All the spectra exhibited an absorption band at around 290 nm, which is a typical band, suggesting the presence of chitosan in the system . Surface plasmon resonance (SPR) band between 400 and 430 nm in the UV‐visible spectrum indicates the formation of AgNPs .…”

Section: Resultsmentioning

confidence: 99%

Synthesis and Activity of Escherichia coli on Different Chitosan Nanoparticles

Thomas¹,

Jose

Nandakumar

et al. 2018

Macromolecular Symposia

View full text Add to dashboard Cite

With a view to finding out the antimicrobial activity of nanoparticle against E. coli, the author prepared chitosan nanoparticles (nCHS), modified form using aloe vera (m‐nCHS), hybrid nanoparticles with silver (h‐nCHS) and modified, hybrid form (m,h‐nCHS). The shape and uniformity of the nanoparticles are assessed by transmission electron microscopy and all the nanoparticles are found to be in the nanometer range. The physiochemical properties of the nanoparticles are determined by UV‐Visible spectroscopy, zeta potential analysis, dynamic light scattering measurements, and fourier transform infrared (FTIR) spectroscopic analysis. UV – visible analysis confirms the formation of chitosan nanoparticles and hybrid Ag – chitosan nanoparticles. The stability and size of the nanoparticles are further confirmed by zeta potential and dynamic light scattering measurements. The antibacterial activity of nanoparticle against Escherichia coli (E. coli) is evaluated by calculation of minimum inhibitory concentration. The results showed that antimicrobial activity is significantly enhanced by the aloe vera modification and presence of Ag nanoparticle on chitosan nanoparticle.

show abstract

“…Specifically, several nanosilver formulations have been developed in which the silver is slowly solubilized over an extended period of time, preventing excessive local concentrations [66]. The nanosilver biopolymer composite films can be formed in a variety of shapes that are active against both E. coli and S. aureus for 10 days without cytotoxicity towards osteoblasts [68,73]. Additionally, only 7% by weight of the loaded silver was released from their coatings after 28 days, demonstrating the long-term antibacterial activity potential of their coating [73].…”

Section: Novel Treatment Modalitiesmentioning

confidence: 99%

Current Options and Emerging Biomaterials for Periprosthetic Joint Infection

et al. 2018

View full text Add to dashboard Cite

Recent advancements in local antibiotic delivery platforms for preventing and treating PJI include titanium nanotube arrays, synthetic polymers, resorbable hydrogels, and cyclodextrin-based drug delivery options. In particular, cyclodextrins have facilitated great advancements in other clinical disorders and have demonstrated early promise as a future option in the arena of PJI. Novel treatment modalities for PJI optimize the implant surfaces to prevent bacterial biofilm formation or provide prolonged intra-articular antibiotic dosing to eradicate bacteria.

show abstract

Electrodeposition of chitosan/gelatin/nanosilver: A new method for constructing biopolymer/nanoparticle composite films with conductivity and antibacterial activity

Cited by 68 publications

References 41 publications

Effect of drug incorporation technique and polymer combination on the performance of biopolymeric antifungal buccal films

Effect of drug incorporation technique and polymer combination on the performance of biopolymeric antifungal buccal films

Synthesis and Activity of Escherichia coli on Different Chitosan Nanoparticles

Current Options and Emerging Biomaterials for Periprosthetic Joint Infection

Contact Info

Product

Resources

About