2011
DOI: 10.1111/j.1528-1167.2011.02996.x
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Electroencephalographic characteristics of Dravet syndrome

Abstract: SUMMARYIn Dravet syndrome, interictal and ictal electroencephalography (EEG) recording may remain misleading, and are not specifically altered. Moreover, there is a great polymorphism of clinical and EEG seizure types. Some can be observed in other epileptic syndromes, but others are more specific-particularly the peculiar unilateral seizures, the falsely generalized seizures, probably with a focal onset, and the unstable seizures. In some cases, the ictal manifestations are characterized by the persistent pre… Show more

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Cited by 84 publications
(99 citation statements)
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“…In our series, we have evidence of difficult seizure control in patient 2, who needed multi-therapy, and patient 7 who, at a clinical follow-up at 2 years of age, was experiencing around 20 episodes of myoclonic seizures/day despite being on high doses of sodium valproate. Although no evidence of a contribution of photosensitivity to the outcome worsening can be drawn from present data, worse seizure control was described in BMEI cases when photosensitivity was present [16], possibly due to stimulating behaviours leading to self-induced seizures [17]. When taken together with previous reports [9] our cases highlight that epilepsy in Patau syndrome is not as mild as previously thought [5,7].…”
Section: Discussionmentioning
confidence: 51%
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“…In our series, we have evidence of difficult seizure control in patient 2, who needed multi-therapy, and patient 7 who, at a clinical follow-up at 2 years of age, was experiencing around 20 episodes of myoclonic seizures/day despite being on high doses of sodium valproate. Although no evidence of a contribution of photosensitivity to the outcome worsening can be drawn from present data, worse seizure control was described in BMEI cases when photosensitivity was present [16], possibly due to stimulating behaviours leading to self-induced seizures [17]. When taken together with previous reports [9] our cases highlight that epilepsy in Patau syndrome is not as mild as previously thought [5,7].…”
Section: Discussionmentioning
confidence: 51%
“…Could early-onset photosensitivity disappear as an effect of age, as reported in Dravet syndrome and BMEI cases [17]? In our cohort ages in the two subgroups overlap, and furthermore there are no patients with subsequent disappearance of earlier positive findings.…”
Section: Discussionmentioning
confidence: 96%
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“…8 A Dravet syndrome seizure might be categorized as spontaneous, facilitated, or reflex based on how the seizure What this paper adds…”
Section: Discussionmentioning
confidence: 99%
“…6,8,13 Therefore, neurologists, parents, and carers should be aware that there may be additional seizure provoking factors in Dravet syndrome other than temperature or visual stimuli; avoidance of triggers remains an important strategy to minimize seizures in these patients.…”
Section: Discussionmentioning
confidence: 99%