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Purpose of review There have been significant advancements in depth of anesthesia (DoA) technology. The Anesthesia Patient Safety Foundation recently published recommendations to use a DoA monitor in specific patient populations receiving general anesthesia. However, the universal use of DoA monitoring is not yet accepted. This review explores the current state of DoA monitors and their potential impact on patient safety. Recent findings We reviewed the current evidence for using a DoA monitor and its potential role in preventing awareness and preserving brain health by decreasing the incidence of postoperative delirium and postoperative cognitive dysfunction or decline (POCD). We also explored the evidence for use of DoA monitors in improving postoperative clinical indicators such as organ dysfunction, mortality and length of stay. We discuss the use of DoA monitoring in the pediatric population, as well as highlight the current limitations of DoA monitoring and the path forward. Summary There is evidence that DoA monitoring may decrease the incidence of awareness, postoperative delirium, POCD and improve several postoperative outcomes. In children, DoA monitoring may decrease the incidence of awareness and emergence delirium, but long-term effects are unknown. While there are key limitations to DoA monitoring technology, we argue that DoA monitoring shows great promise in improving patient safety in most, if not all anesthetic populations.
Purpose of review There have been significant advancements in depth of anesthesia (DoA) technology. The Anesthesia Patient Safety Foundation recently published recommendations to use a DoA monitor in specific patient populations receiving general anesthesia. However, the universal use of DoA monitoring is not yet accepted. This review explores the current state of DoA monitors and their potential impact on patient safety. Recent findings We reviewed the current evidence for using a DoA monitor and its potential role in preventing awareness and preserving brain health by decreasing the incidence of postoperative delirium and postoperative cognitive dysfunction or decline (POCD). We also explored the evidence for use of DoA monitors in improving postoperative clinical indicators such as organ dysfunction, mortality and length of stay. We discuss the use of DoA monitoring in the pediatric population, as well as highlight the current limitations of DoA monitoring and the path forward. Summary There is evidence that DoA monitoring may decrease the incidence of awareness, postoperative delirium, POCD and improve several postoperative outcomes. In children, DoA monitoring may decrease the incidence of awareness and emergence delirium, but long-term effects are unknown. While there are key limitations to DoA monitoring technology, we argue that DoA monitoring shows great promise in improving patient safety in most, if not all anesthetic populations.
Background Lesch-Nyhan syndrome (LNS) is a rare congenital disorder, characterized by self-aggression, self-mutilation, choreoathetosis, and intellectual abnormalities. Ambulatory general anesthesia in LNS children presents a range of challenges. We report a child with LNS who received dental treatment in our ambulatory dental center. Case presentation A 6-year-old boy with LNS was scheduled to undergo treatment for multiple dental caries under ambulatory general anesthesia. To ensure a smooth process, we implemented specific measures for difficult airway management, prevented nausea, vomiting, and pulmonary aspiration, and balanced the use of anesthetic drugs. Post-treatment, the serum uric acid, serum creatinine, and blood urea nitrogen levels remained normal. The entire anesthesia process was complication-free and the child was discharged on the same day. Additionally, we conducted a review and analysis of relevant literature from PubMed and Google Scholar to summarize the anesthetic management experiences in such cases. Conclusion This report details the first successful ambulatory dental general anesthesia for a child with LNS. The management of ambulatory anesthesia for LNS cases is challenging. Despite achieving a positive recovery through comprehensive perioperative management, individualized anesthetic selection and the long-term recovery of the child demand further exploration and research to provide more effective guidance for future clinical practice.
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