Electroencephalographic Studies in Diabetes Mellitus

The Syndrome of Narcolepsy and Diabetogenic Hyper‐insulinism in the American Negro: Important Clinical, Social and Public Health Aspects

“…Such metabolic stress probably begins as early as the neonatal period. These convictions are supported by the foregoing clinical and electroencephalographic observations, and comparable data obtained by others on diabetic patients experiencing severe insulin reactions (38), patients with functioning islet‐cell tumors (39, 40), and patients with petit mal epilepsy (41). It is also highly pertinent that: 1) several narcoleptic diabetic patients who scrupulously avoided insulin reactions (even to the point of defying medical counsel to increase their dosage of insulin because of the feared reactions that inevitably ensued) were found to be free of cerebral dysrhythmias, and 2) improvement of both narcolepsy and dysrhythmias was repeatedly noted after the institution of a corrective diet (see ).…”

EEG studies on cases of juvenile diabetes mellitus of long duration

“…Published data on the frequency of abnormal EEGs in adult diabetics is both limited and contradictory. GREENBLATT et al (5) stated in 1946 that abnormal EEGs were found in 3 (8 per cent) of 40 insulin-treated diabetics between 18 and 49 years of age who suffered from "uncomplicated diabetes" and had a duration of diabetes varying between one week and 21 years, and also that abnormal EEGs were found in 18 of 35 patients (51 per cent) between the ages of 14 and 54 with "repeated severe insulin reactions" and a duration of illness varying between 5 months and 20 years. The average age of patients belonging to these two groups was 34 and 25.7 years respectively.…”

The Impact of Diabetes on the CNS

“…Several early (181)(182)(183)(184) and some recent (185)(186)(187) reports suggest EEG abnormalities are more common in people with diabetes. The import for clinical medicine of these findings is unclear.…”