Electrogastrography: A Seductive Promise, Only Partially Kept

Bortolotti, Mauro

doi:10.1111/j.1572-0241.1998.01791.x

Cited by 50 publications

(63 citation statements)

References 26 publications

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“…In a study by Liang and Chen (1997), it was shown that the detectability of gastric slow wave propagation from cutaneous EGG is dependent on the thickness of the abdominal wall and on the propagation velocity of the serosal slow wave. Another disadvantage of this method which was pointed out, among others, by Bortolotti (1998) is that the practicality of using EGG to detect alterations in slow wave frequency due to tachy-and bradygastria remains problematic in spite of considerable recent progress to improve filtering and analysis methods for this clinical procedure. Reservations concerning the significance of EGG as a diagnosis tool were also expressed by Camilleri et al (1998), who indicated that the precise meaning of dysrhythmias, signal amplitude changes and the duration of such abnormalities relative to gastric emptying as quantified by EGG remain to be clarified.…”

Section: Motivation and Purposementioning

confidence: 99%

Magnetogastrographic detection of gastric electrical response activity in humans

2006

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The detection and characterization of gastric electrical activity has important clinical applications, including the early diagnosis of gastric diseases in humans. In mammals, this phenomenon has two important features: an electrical control activity (ECA) that manifests itself as an electric slow wave (with a frequency of 3 cycles per minute in humans) and an electrical response activity (ERA) that is characterized by spiking potentials during the plateau phase of the ECA. Whereas the ECA has been recorded in humans both invasively and non-invasively (magnetogastrography-MGG), the ERA has never been detected non-invasively in humans before. In this paper, we report on our progress towards the non-invasive detection of ERA from the human stomach using a procedure that involves the application of principal component analysis to MGG recordings, which were acquired in our case from ten normal human patients using a Superconducting QUantum Interference Device (SQUID) magnetometer. Both pre-and post-prandial recordings were acquired for each patient and 20 min of recordings (10 min of pre-prandial and 10 min of post-prandial data) were analysed for each patient. The mean percentage of ECA slow waves that were found to exhibit spikes of suspected ERA origin was 41% and 61% for pre-and post-prandial recordings, respectively, implying a 47% ERA increase post-prandially (P < 0.0001 at a 95% confidence level). The detection of ERA in humans is highly encouraging and points to the possible use of non-invasive ERA recordings as a valuable tool for the study of human gastric disorders.

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Section: Motivation and Purposementioning

confidence: 99%

Magnetogastrographic detection of gastric electrical response activity in humans

2006

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“…Studies have shown a good correlation between cutaneous EGG recordings and myoelectric signals recorded from gastric serosal leads [2] . However, there are major concerns regarding the clinical usefulness of this noninvasive procedure [3] . EGG has been advocated as a diagnostic test in the clinical evaluation of patients with unexplained nausea, vomiting and other dyspeptic symptoms to gain insight into the mechanisms of symptom generation.…”

Section: Introductionmentioning

confidence: 99%

Electrogastrography: Poor correlation with antro-duodenal manometry and doubtful clinical usefulness in adults

Abid

Lindberg

2007

WJG

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AIM:To investigate if there is a correlation between electrical activity measured by electrogastrography (EGG) and contractile activity of the stomach as measured by antroduodenal manometry (ADM). We also studied whether the underlying motility disorder could be predicted from EGG parameters. METHODS:We compared 21 parameters measured from EGG with 8 parameters measured from ADM. The ability of EGG to identify the underlying diagnosis was tested by comparing EGG parameters for each diagnosis group against other patients. The study comprised recordings from 148 patients and 125 females. Their median age was 45 (range 17-76) years. RESULTS:We found few and weak correlations between EGG and ADM. Specifically the correlation between parameters reflecting the response to meal was poor (r = -0.07, P = 0.39). The discriminatory power of EGG for underlying motility disorder was also low. Patients with slow transit constipation (STC) showed a lower postprandial power in normogastric (3.7 ± 0.5

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“…Cutaneous EGG recordings offer a non-invasive approach to detect and characterise gastric slow wave recordings. At present, however, EGG has limited use in routine clinical care, and is best summarised by Bortolotti et al [7] as "a seductive promise, only partially kept". Improvements in recording reliable slow wave signals has allowed for the development of automated analysis methods.…”

Section: Discussionmentioning

confidence: 98%

“…EGG is not widely used in clinical practice due to difficulties in relating the signals to the underlying slow wave events [7]. In terms of recording specifications, a set of guidelines has been prescribed by the American Motility Society Taskforce to be adhered [8].…”

Section: Introductionmentioning

confidence: 99%

A system for automated quantification of cutaneous electrogastrograms

Paskaranandavadivel

Bull

Parsell

et al. 2015

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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Clinical evaluation of cutaneous electrogastrograms (EGG) is important for understanding the role of slow waves in functional motility disorders and may be a useful diagnostic aid. An automated software package has been developed which computes metrics of interest from EGG and from slow wave recordings from the gastric mucosa and serosa in a reliable and efficient manner. In particular, the frequency and amplitude of the gastric slow waves were computed, after which signal integrity checks were performed to assess if the signals are valid. For validation, manual estimates of the frequency and amplitude were compared to automated estimates. The methods were packaged into a software executable which processes the data and presents the results in an intuitive graphical and a spreadsheet formats. Automated EGG analysis allows for clinical translation of bio-electrical analysis for potential diagnostics, as commonly used in the cardiac field.

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Electrogastrography: A Seductive Promise, Only Partially Kept

Cited by 50 publications

References 26 publications

Magnetogastrographic detection of gastric electrical response activity in humans

Magnetogastrographic detection of gastric electrical response activity in humans

Electrogastrography: Poor correlation with antro-duodenal manometry and doubtful clinical usefulness in adults

A system for automated quantification of cutaneous electrogastrograms

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