Electrolytes of the gastric juice in health and gastroduodenal diseases

Meeroff, J. C.; Rofrano, Jorge Alberto; Meeroff, M

doi:10.1007/bf01073337

Cited by 17 publications

(12 citation statements)

References 21 publications

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“…Relative to the two beer-spoiling isolates, KB290 plasmids pKB290-2 and -3 encode a number of transporters involved in ion and proton transport which likely contribute to efficient proton motive force regulation when growing in the presence of highly concentrated electrolytes of gastric and intestinal juices (Meeroff et al 1973). Other transporters are involved in the uptake of amino acids or peptides, presumably allowing KB290 to utilize peptides made available by the enzymatic action of pepsin in gastric juices (Fruton, 2002).…”

Section: Plasmids In Lab From Beer and Gastrointestinal Environmentsmentioning

confidence: 99%

Comparative genomic and plasmid analysis of beer-spoiling and non-beer-spoilingLactobacillus brevisisolates

Bergsveinson

Ziola

2017

Can. J. Microbiol.

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Beer-spoilage-related lactic acid bacteria (BSR LAB) belong to multiple genera and species; however, beer-spoilage capacity is isolate-specific and partially acquired via horizontal gene transfer within the brewing environment. Thus, the extent to which genus-, species-, or environment- (i.e., brewery-) level genetic variability influences beer-spoilage phenotype is unknown. Publicly available Lactobacillus brevis genomes were analyzed via BlAst Diagnostic Gene findEr (BADGE) for BSR genes and assessed for pangenomic relationships. Also analyzed were functional coding capacities of plasmids of LAB inhabiting extreme niche environments. Considerable genetic variation was observed in L. brevis isolated from clinical samples, whereas 16 candidate genes distinguish BSR and non-BSR L. brevis genomes. These genes are related to nutrient scavenging of gluconate or pentoses, mannose, and metabolism of pectin. BSR L. brevis isolates also have higher average nucleotide identity and stronger pangenome association with one another, though isolation source (i.e., specific brewery) also appears to influence the plasmid coding capacity of BSR LAB. Finally, it is shown that niche-specific adaptation and phenotype are plasmid-encoded for both BSR and non-BSR LAB. The ultimate combination of plasmid-encoded genes dictates the ability of L. brevis to survive in the most extreme beer environment, namely, gassed (i.e., pressurized) beer.

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Section: Plasmids In Lab From Beer and Gastrointestinal Environmentsmentioning

confidence: 99%

Comparative genomic and plasmid analysis of beer-spoiling and non-beer-spoilingLactobacillus brevisisolates

Bergsveinson

Ziola

2017

Can. J. Microbiol.

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“…Die Operation fand planmäßig am 11.11.2004 Originalarbeiten und Übersichten 0,45-1 % aller Divertikel des Magendarmtraktes aus [23]. Ihre genaue Inzidenz ist nicht bekannt.…”

Section: Fallberichte Fallunclassified

“…Ihre genaue Inzidenz ist nicht bekannt. In der Literatur werden Inzidenzen je nach Messmethode in Autopsien mit 0,01-0,12 %, in Röntgenuntersuchungen des oberen GI-Traktes mit 0,01-0,65 % und in Gastroskopien mit 0,01-2,6 % angegeben [10,14,18,19,23,24,30].…”

Section: Fallberichte Fallunclassified

“…Zu rund 75 % treten Magendivertikel (wie in unseren beiden Fällen auch) subkardial an der Magenhinterwand kurz unterhalb des gastroösophagealen Überganges und nahe der kleinen Kurvatur auf. Weitere 15 % wurden im präpylorischen Antrum gefunden, die restlichen 10 % verteilen sich auf andere Magenanteile [9,10,13,23,24,26,28,30]. Es wird vermutet, dass die meisten Divertikel subkardial aufgrund einer relativen anatomischen Schwäche der Magenwand auftreten, hervorgerufen durch das "Aufsplitten" der longitudinalen Muskelfasern an jener Stelle, so dass dort lediglich die zirkuläre Muskelschicht unter der Mukosa liegt [5,23,30,31].…”

Section: Lokalisationunclassified

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Die laparoskopische Resektion von Magendivertikeln: zwei Fallberichte

Schiller¹,

Roggendorf²,

Delker-Wegener³

et al. 2007

Zentralbl Chir

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Gastric diverticula are rare. In the literature the mentioned incidences vary between 0.01 % and 2.6 % depending on the method of detection. Until now the laparoscopic treatment of gastric diverticula is reported worldwide by eight authors (eight laparoscopic resections and one laparoscopic invagination with oversewing). Between September 2000 and November 2004 we have operated upon two patients laparoscopically for a gastric diverticulum. In two case reports we describe our operative and perioperative procedure. In both cases the gastric diverticulum was resected with a linear stapling device. In the second patient we did simultaneously a laparoscopic 360 degrees -Nissen-fundoplicatio plus dorsal hiatorrhaphy and fundopexy because of reflux disease based on a cardia insufficiency. The dates of the literature concerning incidence, localisation, classifications, symptoms, diagnostic and therapy are summarized and discussed. Our two case reports show, like the cases mentioned in the literature, that symptomatic gastric diverticula can be treated by laparoscopic resection with very good results.

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“…The process of 'back diffusion' underlying tire increased disappearance of acid from instilled acid solutions was considered, by extrapolation, to explain the abnormally low acid concentration of the juice secreted by chemically treated, or injured, gastric mucosa. The hypothesis of 'back-diffusion' has been further extended (82) to explain the observation that patients with gastric ulcer or with gastritis secrete gastric juice which contains abnormally little acid and abnormal ly high concentrations of sodium (11,106). As a result of re-emphasis by Daven port (39), increased 'leakiness' of the gastric mucosa with excessive 'back-dif fusion' o f acid into the mucosa was sought, and found, in human gastric mucosal diseases (2 4,2 5 ,4 8 , 85, 88, 117) and considered responsible for the 'apparently' impaired secretion of acid by patients with gastric ulcer -'apparently' impaired, because it was proposed that the stomach actually secreted acid normally in response to stimulants but lost acid so rapidly as a result o f 'back-diffusion' that only abnormally small amounts of acid could be recovered from the gastric lumen.…”

Section: Introductionmentioning

confidence: 99%

Back-Diffusion – Fact or Fiction?

Þjóðleifsson

Wormsley

1977

Digestion

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Alterations in the concentration of acid in gastric juice secreted at different flow rates and disappearance of acid from the gastric lumen, when the gastric mucosa is exposed to acid luminal contents, have been interpreted as indicating ‘back-diffusion’ of acid into the gastric mucosa from the luminal contents. The loss of acid from the gastric contents increases when the mucosa is exposed to certain drugs or is diseased, giving rise to the suggestion that the increased degree of ‘back-diffusion’ of acid indicates mucosal damage, reflecting a breakdown of the gastric mucosal ‘barrier’ to back-diffusion of acid from the gastric lumen. The change in the ‘barrier’ properties of the gastric mucosa has been found to be associated with change in the electrical properties of the mucosa, so that alterations of the transmucosal potential difference has been considered to denote gastric mucosal damage. The case for every one of these hypotheses and for their underlying assumptions is discussed and found wanting for lack of direct evidence.

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Electrolytes of the gastric juice in health and gastroduodenal diseases

Cited by 17 publications

References 21 publications

Comparative genomic and plasmid analysis of beer-spoiling and non-beer-spoilingLactobacillus brevisisolates

Comparative genomic and plasmid analysis of beer-spoiling and non-beer-spoilingLactobacillus brevisisolates

Die laparoskopische Resektion von Magendivertikeln: zwei Fallberichte

Back-Diffusion – Fact or Fiction?

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