Electromagnetic navigation bronchoscopy for the diagnosis of
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              <i>A</i>
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            <i>spergillus</i>
            infection

Chan, Samuel; Pumar, Marsus; Leong, Steven; Horvath, Robert; Marshall, Henry; Yang, Ian A.; Fong, Kwun M.

doi:10.1002/rcr2.39

Cited by 2 publications

(4 citation statements)

References 5 publications

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“…In our practice we routinely send samples for microbiological investigations including mycobacterial and fungal studies. Fungal infections can be diagnosed from these samples 20 . In this case report, severe emphysema also precluded a percutaneous, transpleural approach.…”

Section: Enb In Infectionmentioning

confidence: 82%

Navigation bronchoscopy: A new tool for pulmonary infections

Ashraf

Lau

2019

Medical Mycology

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Infections remain a common cause of lung nodules, masses, and cavities. Safe tissue sampling is required to establish a diagnosis, differentiate between malignant and infectious causes, and provide microbiological material for characterization and sensitivity analysis. Tissue samples could be obtained bronchoscopically, percutaneously, or through surgical biopsy. Among these, bronchoscopy is the safest by avoiding the complications of pleural and chest wall puncture including pneumothorax, pain, pleural contamination and empyema, and hemothorax. However, the diagnostic yield with conventional bronchoscopy for small, peripheral lesions is poor. Electromagnetic navigation bronchoscopy (ENB) is a technique where the bronchoscope and working channel are guided through the bronchial tree to accurately reach a peripheral lesion. It dramatically improves on the diagnostic yield of peripheral lesions especially of small lesions, and its role has developed beyond diagnosis to treatment enablement and to direct therapy. Its role in infection is less defined, but it has value especially in the diagnosis of fungal and mycobacterial infections and in cavitating lesions. This review will explore what electromagnetic navigation bronchoscopy is, its use in diagnosis and therapy, and its role in the management of pulmonary infections. The potential for local therapy delivery for infection is also discussed.

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Section: Enb In Infectionmentioning

confidence: 82%

Navigation bronchoscopy: A new tool for pulmonary infections

Ashraf

Lau

2019

Medical Mycology

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“…To the Editor: Tracheoesophageal fistulas (TEFs) are either congenital (seen in roughly 0.04% of newborn infants) or acquired. 1 Acquired TEFs in adults can either be "benign" TEFs resulting from iatrogenic insult such as airway procedures or endotracheal cuff injury in prolonged intubation, or due to malignancy, primarily esophageal cancer. 1,2 Although uncommon, TEFs carry significant morbidity from recurrent aspiration pneumonia and malnutrition which can decrease patient quality of life.…”

Section: Novel Use Of a Nasal Septal Occludermentioning

confidence: 99%

“…1 Acquired TEFs in adults can either be "benign" TEFs resulting from iatrogenic insult such as airway procedures or endotracheal cuff injury in prolonged intubation, or due to malignancy, primarily esophageal cancer. 1,2 Although uncommon, TEFs carry significant morbidity from recurrent aspiration pneumonia and malnutrition which can decrease patient quality of life. 3 Surgical correction is deemed definitive, however, this carries significant morbidity and is often limited by underlying…”

Section: Novel Use Of a Nasal Septal Occludermentioning

confidence: 99%

“…Electromagnetic navigational bronchoscopy (ENB) is increasingly used for both diagnostic and therapeutic reasons. Although there have been reports of both diagnosis1 and drainage of fungal cavitary lesions2 using ENB technique as well as endobronchial ultrasound (EBUS)-guided intracavitary injection of liposomal amphotericin B,3 our literature search yielded no reports of any such therapeutic use of the robotic-assisted navigation bronchoscopy (RANB) systems for the same. We present the first case report where RANB technique was used to directly inject liposomal amphotericin B into a chronic invasive aspergillus lesion.…”

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confidence: 99%

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