Electromechanical Properties of Carbon Nanotube Infused Polyacrylamide Hydrogel

Jackson, Nathan; Sheehan, Athena; Hasan, Maksudul; Stam, Frank; Razeeb, Kafil M.

doi:10.1002/adv.21484

Cited by 7 publications

(5 citation statements)

References 30 publications

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“…A value of ν polyacrylamide = 0.45 was used in the calculation. 38 As expected, the gel elastic modulus increases with increasing the ratio of acrylamide: biacrylamide which correspond to a higher cross-linking density. Accordingly, the computed stiffness of the FN-PAA substrates employed in this study are 1.5 and 17.7 kPa, which correspond to the stiffness of adipose and skeletal muscle tissue (i.e., soft tissues) respectively.…”

Section: Resultssupporting

confidence: 64%

“…The Young’s modulus, E , can be computed from the measured average G * with the following equation: E = 2G*(1+ ν), where ν is the Poisson ratio of polyacrylamide. A value of ν polyacrylamide = 0.45 was used in the calculation . As expected, the gel elastic modulus increases with increasing the ratio of acrylamide: biacrylamide which correspond to a higher cross-linking density.…”

Section: Resultsmentioning

confidence: 81%

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Soft Material Approach to Induce Oxidative Stress in Mesenchymal Stem Cells for Functional Tissue Repair

Yang

Nguyen

Leong

et al. 2016

ACS Appl. Mater. Interfaces

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Biomimicking hydrogel-based cell culture platforms with physiologically relevant stiffness are powerful tools to modulate the behaviors of stem cells. Herein, the use of fibronectin-conjugated polyacrylamide (PAA) hydrogel biointerface is exploited to modulate the intracellular oxidative stress of human bone marrow derived mesenchymal stem cells (MSCs). We show that compliant culture surface with kPa range matrix stiffness can augment the expression level of reactive oxygen species (ROS) in MSCs by approximately 2-4 fold compared with cells grown on conventional FN coated glass control surface in a noncytotoxic manner. Via an unbiased proteomics approach and mechanistic studies, we show that the secretion level of a sub series of "mechano-sensitive" chemokines and trophic factors is heavily dependent on the PAA matrix stiffness mediated ROS level. Importantly, the secretome harvested from the cells that were grown on the PAA hydrogel was found to enhance wound healing in both in vitro and in vivo full thickness mouse excisional wound model. The devised "soft approach" to induce oxidative stress in MSCs is posited to pave the way for novel cell-free therapeutic interventions targeting a wide variety of diseases and to foster functional tissue repair.

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Section: Resultssupporting

confidence: 64%

Section: Resultsmentioning

confidence: 81%

Soft Material Approach to Induce Oxidative Stress in Mesenchymal Stem Cells for Functional Tissue Repair

Yang

Nguyen

Leong

et al. 2016

ACS Appl. Mater. Interfaces

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“…Electrically conducting particles such as carbon nanotubes [8,9], metallic particles, and liquid metal have been used to create composite materials with increased conductivity [10]. Silver nanoparticles are of particular interest due to their high electrical conductivity properties.…”

Section: Introductionmentioning

confidence: 99%

Multi-functional 0–3 composite polyimide films for microsystem applications

Güler

Vazquez

Jackson

2023

Smart Mater. Struct.

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The development of smart functional thin film composite polymer materials has been extensively investigated over the past decade. However, the polymers poor thermal properties have negatively impacted the manufacturing complexity resulting in limited success in microsystem applications. This paper investigates the development of MEMS compatible flexible multi-functional 0-3 composite materials consisting of a high temperature polyimide (PI) matrix with lead zirconate titanate (PZT) and silver (Ag) nanoparticles. Microfabrication manufacturing methods were investigated to deposit the thin film composites and they were characterized with varying concentrations of nanoparticles. Piezoelectric composites with room temperature d33,f values up to 23 pC N-1 were demonstrated. In addition, Ag-PI composites demonstrated electrical conductivity values of 11 S m-1 at room temperature. The composites maintain relatively high mechanical flexibility and temperature properties from the PI matrix. Integration of the nanoparticles in the films were validated through X-ray diffraction and scanning electron microscopy images. The PZT-PI composites demonstrated an increase in piezoelectric values under elevated temperatures up to 300°C. Capacitor and energy harvesting devices consisting of three layers of composite films (Ag-PI/PZT-PI/Ag-PI) were microfabricated to validate the materials functionality and integration into microsystem-based devices. These novel flexible high temperature films could have wide use in next generation electronics.

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“…However, the systems formed from the combination of starch or/and polyacrylamide with CNTs [25][26][27][28][29] are usually obtained in an aqueous medium, assisting mixing, e.g. with sonication.…”

Section: Nanokompozytowe Kopolimery Szczepione Skrobi Z Nanorurkami Węglowymi -Synteza I Efektywność Flokulacyjnamentioning

confidence: 99%

Nanocomposite starch graft copolymers with carbon nanotubes - synthesis and flocculation efficiency

Schmidt

2020

Polimery

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Nanocomposite flocculants based on polyacrylamide-grafted starch copolymers with carbon nanotubes (PAM-St-CNT) were prepared using natural polymer -potato starch (St), acrylamide (AM) as monomer and CNTs by in situ polymerization process. The effect of monomer to starch molar ratio, dose of flocculants and content of CNTs in composition on flocculation efficiency were investigated. All materials were characterized by FT-IR (Fourier transform infrared spectroscopy), TGA (thermogravimetric analysis) and DSC (differential scanning calorimetry) methods. An aqueous suspension of kaolin was used for the flocculation studies. The flocculation effectiveness was evaluated on the basis of reduction of suspension absorption and the sludge volume. It was found that synthesized nanocomposites PAM--St-CNT exhibit satisfactory flocculating properties.

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Electromechanical Properties of Carbon Nanotube Infused Polyacrylamide Hydrogel

Cited by 7 publications

References 30 publications

Soft Material Approach to Induce Oxidative Stress in Mesenchymal Stem Cells for Functional Tissue Repair

Soft Material Approach to Induce Oxidative Stress in Mesenchymal Stem Cells for Functional Tissue Repair

Multi-functional 0–3 composite polyimide films for microsystem applications

Nanocomposite starch graft copolymers with carbon nanotubes - synthesis and flocculation efficiency

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