Electron impact mass spectrometry of 3‐methyl‐4‐benzylideneamine‐5‐styrylisoxazoles. II

Abstract

The mass spectra of a series of substituted 3‐methyl‐4‐benzylideneamine‐5‐styrylisoxazoles are reported and discussed. The spectra of these isoxazoles show a characteristic fragmentation pattern different from the 5‐styryl‐4‐nitroisoxazoles. Perhaps this is due to the presence of the Schiff base at position 4.

ChemInform Abstract: ORTHO EFFECTS IN 3‐METHYL‐5‐(O‐R‐STYRYL)‐4‐AMINOISOXAZOLES ON ELECTRON IMPACT. PART 3.

“…Diarylethylene and triarylethylene analogs represent a series of compounds of considerable medicinal interest mainly as post-coital antifertility agents (3). This induces us to report the synthesis and mass spectrometry studies of a closely related family of compounds of the general structure I (4,5). In this paper we wish to report the mass spectral fragmentation patterns of 4-aminoisoxazoles I (Scheme 1; R1 = NH, and R, = H, Me, OH, OMe, OEt, CI, OAc, OBz).…”