2004
DOI: 10.1152/ajpcell.00248.2003
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Electron microprobe analysis of ouabain-exposed ciliary epithelium: PE-NPE cell couplets form the functional units

Abstract: . Electron microprobe analysis of ouabain-exposed ciliary epithelium: PE-NPE cell couplets form the functional units. Am J Physiol Cell Physiol 286: C1376 -C1389, 2004. First published February 4, 2004 10.1152/ajpcell. 00248.2003.-Aqueous humor is secreted by the bilayered ciliary epithelium. Solutes and water enter the pigmented ciliary epithelial (PE) cell layer, cross gap junctions into the nonpigmented ciliary epithelial (NPE) cell layer, and are released into the aqueous humor. Electrical measurements su… Show more

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Cited by 22 publications
(15 citation statements)
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“…Both anteriorly and posteriorly, ouabain produced cell shrinkage, as monitored by (Na ϩ K)/P. All ouabaintriggered changes in composition were substantially greater in the anterior than posterior region (Table 1), confirming our earlier observation (33).…”
Section: Resultssupporting
confidence: 86%
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“…Both anteriorly and posteriorly, ouabain produced cell shrinkage, as monitored by (Na ϩ K)/P. All ouabaintriggered changes in composition were substantially greater in the anterior than posterior region (Table 1), confirming our earlier observation (33).…”
Section: Resultssupporting
confidence: 86%
“…3 and Table 1). More prolonged exposure to ouabain leads to entry of Cl Ϫ together with Na ϩ into the cells (33). In the present study, the reduction in K/P was ϳ0.4 posteriorly, slightly less than one-half the fall in K/P noted anteriorly ( Fig.…”
Section: Resultssupporting
confidence: 41%
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