Electron Microscopic Assay of Bacterial Biofilm Formed on Indwelling Urethral Catheters

Azmy, Magda; Nawar, Nada; Mohiedden, Mona

doi:10.12816/0033967

Cited by 1 publication

(1 citation statement)

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“…101 Candida biofilms are readily detected on indwelling catheters by scanning electron microscopy. 102 C. albicans adheres poorly to the bladder mucosa, and risk for Candida UTI increases sharply in the presence of an indwelling catheter. 103,104 A recent ex vivo study showed that a C. albicans CAUTI isolate binds to urinary catheters via fibrinogen.…”

Section: Antimicrobial-coated Urinary Cathetersmentioning

confidence: 99%

Pathophysiology, Treatment, and Prevention of Catheter-Associated Urinary Tract Infection

Flores-Mireles

Hreha

Hunstad

2019

Topics in Spinal Cord Injury Rehabilitation

128

107

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Urinary tract infections (UTIs) are among the most common microbial infections in humans and represent a substantial burden on the health care system. UTIs can be uncomplicated, as when affecting healthy individuals, or complicated, when affecting individuals with compromised urodynamics and/or host defenses, such as those with a urinary catheter. There are clear differences between uncomplicated UTI and catheter-associated UTI (CAUTI) in clinical manifestations, causative organisms, and pathophysiology. Therefore, uncomplicated UTI and CAUTI cannot be approached similarly, or the risk of complications and treatment failure may increase. It is imperative to understand the key aspects of each condition to develop successful treatment options and improve patient outcomes. Here, we will review the epidemiology, pathogen prevalence, differential mechanisms used by uropathogens, and treatment and prevention of uncomplicated UTI and CAUTI.

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Section: Antimicrobial-coated Urinary Cathetersmentioning

confidence: 99%