Electron microscopic observations on herpes-type virus-related structures in the frog renal adenocarcinoma

Concomitant herpes-like virus infections in hatchery-reared larvae and nursery-cultured spat Crassostrea gigas and Ostrea edulis

“…Tubular structures were described from herpes-like virus infections of adult Crassostrea virginica (Farley et al 1972), in the larval stages of the flat oyster Tiostrea chilensis (Hine et al 1998) and in ranid herpesvirus 1 infections (Stackpole & Mizell 1968). The tubular structures were composed of an outer tubule that was 45 to 55 nm in diameter containing a tubular core 25 nm in diameter and have been observed in both larvae and spat Crassostrea gigas and Ostrea edulis.…”

“…Accumulations of naked nucleocapsids in the stroma of infected oyster cell cytoplasm were reported in both oyster species in larvae and spat and can be interpreted as advanced stages of cytopathic changes (Friedmann et al 1976, Tralka et al 1977. Extracellular naked nucleocapsids were also observed in both oyster species and may derive from lysed infected nuclei.Tubular structures were described from herpes-like virus infections of adult Crassostrea virginica (Farley et al 1972), in the larval stages of the flat oyster Tiostrea chilensis (Hine et al 1998) and in ranid herpesvirus 1 infections (Stackpole & Mizell 1968). The tubular structures were composed of an outer tubule that was 45 to 55 nm in diameter containing a tubular core 25 nm in diameter and have been observed in both larvae and spat Crassostrea gigas and Ostrea edulis.…”

Unusual Intranuclear Tubular Structures Associated with the Maturation of Herpesvirus saimiri in Monkey Kidney Cell Cultures

“…With infectious laryngotracheitis virus, Marek's disease herpesvirus, and the Lucke tumour herpesvirus such tubular structures found in the nucleus have been likened, when sectioned in certain planes for electron microscopy, to linear assemblies resembling immature virus particles in construction (Watrach, 1962;Stackpole and Mizell, 1968;Campbell and Woode, 1970), although somewhat variable in cross section and elongated. Where negative contrast preparations have been studied this idea has been supported by the finding of spiral arrays of capsomeres on the surface of the tubules, identical to those covering the immature virus particles (Stackpole and Mizell, 1968).…”

“…With infectious laryngotracheitis virus, Marek's disease herpesvirus, and the Lucke tumour herpesvirus such tubular structures found in the nucleus have been likened, when sectioned in certain planes for electron microscopy, to linear assemblies resembling immature virus particles in construction (Watrach, 1962;Stackpole and Mizell, 1968;Campbell and Woode, 1970), although somewhat variable in cross section and elongated. Where negative contrast preparations have been studied this idea has been supported by the finding of spiral arrays of capsomeres on the surface of the tubules, identical to those covering the immature virus particles (Stackpole and Mizell, 1968). However, the other herpesvirus-associated structures do not seem to be related to recognizable virus components since they are either altered spindle tubules (Fawcett, 1956;Epstein, Achong and Barr, 1964), or membranes within the nucleoplasm (Epstein et al, 1968;Nii et al, 1968), or microtubular lattices (Murphy et al, 1967;Couch and Nahmias, 1969), or fibrils accompanied by repeating sub-units (Chitwood and Bracken, 1964;Campbell and Woode, 1970).…”

“…THE development of a number of herpesviruses is often accompanied by the appearance of one or other of a variety of bizarre tubular or membranous structures in the infected cells (Fawcett, 1956;Watrach, 1962;Chitwood and Bracken, 1964;Epstein, Achong and Barr, 1964; Murphy, Harrison and Whitfield, 1967;Epstein et al, 1968;Nii, Morgan and Rose, 1968;Stackpole and Mizell, 1968;Couch and Nahmias, 1969;Campbell and Woode, 1970;Heine and Hinze, 1972;McKinnell and Ellis, 1972). With infectious laryngotracheitis virus, Marek's disease herpesvirus, and the Lucke tumour herpesvirus such tubular structures found in the nucleus have been likened, when sectioned in certain planes for electron microscopy, to linear assemblies resembling immature virus particles in construction (Watrach, 1962;Stackpole and Mizell, 1968;Campbell and Woode, 1970), although somewhat variable in cross section and elongated.…”